Antibody response to and immunity induced by Corynebacterium pyogenes vaccine

Show simple item record Cameron, Colin McKenzie Botha, Wilna F. Smit, B.H.J.
dc.contributor.editor Bigalke, R.D.
dc.contributor.editor Cameron, Colin McKenzie
dc.contributor.editor Gilchrist, Frances M.C.
dc.contributor.editor Morren, A.J.
dc.contributor.editor Verster, Anna J.M.
dc.contributor.editor Verwoerd, Daniel Wynand
dc.contributor.editor Walker, Jane B.
dc.contributor.other De Kock, V.E. 2016-07-06T09:55:26Z 2016-07-06T09:55:26Z 2016 1976
dc.description The articles have been scanned in colour with a HP scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to final presentyation PDF-Format. en_ZA
dc.description.abstract A procedure is described for producing a high quality C. pyogenes vaccine. A satisfactory antibody response was obtained by administering 3 subcutaneous injections of vaccine at 10-day intervals, using doses of 2,0 ml for rabbits, 5,0 ml for sheep and 10,0 ml for cattle. The titres resulting from this procedure compared favourably with those obtained from following the more intensive schedule and higher doses of vaccine recommended by the British Veterinary Codex. The antibody response was at its best 1-2 months after immunization but dropped to a plateau 6 months after immunization. Mice were also successfully immunized against challenge with 1, 5 x 10⁸ organisms by the application of 3 doses of vaccine administered at 10-day intervals. en_ZA
dc.identifier.citation Cameron, CM, Botha, WF & Smit, BHJ 1976, 'Antibody response to and immunity induced by Corynebacterium pyogenes vaccine’, The Onderstepoort Journal of Veterinary Research, vol. 43, no. 3, pp. 97-103. en_ZA
dc.identifier.issn 0330-2465
dc.language.iso en en_ZA
dc.publisher Published by The Government Printer, Pretoria en_ZA
dc.rights ©1976 ARC-Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©2016 University of Pretoria. Department of Library Services (digital). en_ZA
dc.subject Veterinary medicine en_ZA
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title Antibody response to and immunity induced by Corynebacterium pyogenes vaccine en_ZA
dc.type Article en_ZA

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