The isolation and preliminary genetic classification of temperature-sensitive mutants of bluetongue virus

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Authors

Shipham, S.O.
De la Rey, M.

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Published by The Government Printer, Pretoria

Abstract

Temperature-sensitive mutants of bluetongue virus were isolated and classified in 6 genetic recombination groups. The frequency of recombination varied both within and between groups. The 4 mutagens used viz. nitrous acid, N-methyl-N-nitroso-N-nitroguanidine, proflavine and 5-fluorouracil were found to differ in their efficacy. The period of incubation required for maximum recombination was 48 h at 28 °C.

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Keywords

Veterinary medicine

Sustainable Development Goals

Citation

Shipham, SO & De la Rey, M 1976, 'The isolation and preliminary genetic classification of temperature-sensitive mutants of bluetongue virus’, Onderstepoort Journal of Veterinary Research, vol. 43, no. 4, pp. 189-192.