The end of the line? A case of drug resistance to third-line antiretroviral therapy

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Authors

Rossouw, Theresa M.
Hitchcock, Sonia Anne
Botes, Mariette

Journal Title

Journal ISSN

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Publisher

Health and Medical Publishing Group

Abstract

HIV drug resistance has been described in all antiretroviral drug classes and threatens the long-term success of HIV treatment. Here, we describe the first reported case of acquired resistance to the integrase strand transfer inhibitors in South Africa. This case illustrates the dilemma of treatment in the context of inadequate adherence and poor psychosocial support and highlights the potential risk of transmission of multidrug-resistant virus.

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Keywords

Treatment, Multidrug-resistant virus, Human immunodeficiency virus (HIV), South Africa (SA), Antiretroviral therapy (ART), multi

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Citation

Rossouw TM, Hitchcock S, Botes M. The end of the line? A case of drug resistance to third-line antiretroviral therapy. S Afr J HIV Med. 2016;17(1), a454. http://dx. DOI.org/ 10.4102/sajhivmed.v17i1.454.