The end of the line? A case of drug resistance to third-line antiretroviral therapy
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Date
Authors
Rossouw, Theresa M.
Hitchcock, Sonia Anne
Botes, Mariette
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group
Abstract
HIV drug resistance has been described in all antiretroviral drug classes and threatens the
long-term success of HIV treatment. Here, we describe the first reported case of acquired
resistance to the integrase strand transfer inhibitors in South Africa. This case illustrates the
dilemma of treatment in the context of inadequate adherence and poor psychosocial support
and highlights the potential risk of transmission of multidrug-resistant virus.
Description
Keywords
Treatment, Multidrug-resistant virus, Human immunodeficiency virus (HIV), South Africa (SA), Antiretroviral therapy (ART), multi
Sustainable Development Goals
Citation
Rossouw TM, Hitchcock S,
Botes M. The end of the line?
A case of drug resistance to
third-line antiretroviral
therapy. S Afr J HIV Med.
2016;17(1), a454. http://dx.
DOI.org/ 10.4102/sajhivmed.v17i1.454.