Standing sedation with medetomidine and butorphanol in captive African elephants (Loxodonta africana)

Show simple item record Lüders, I. Tindall, B Young, D. Van der Horst, G. Botha, S. Luther, I. Maree, L. Bertschinger, Hendrik Jan 2016-05-11T14:46:42Z 2016-03
dc.description.abstract Doses for standing sedation allowing for various procedures in otherwise inaccessible, untrained captive African elephant bulls are presented. Thirty-three standing sedations were performed in 12 males aged 8–30 years (one to four sedations per animal). Each bull received a combination of 0.009 ± 0.002 mg/kg medetomidine and 0.03 ± 0.007 mg/kg butorphanol. Full sedation was reached on average 25.5 min after injection. The addition of hyaluronidase (1000–2000 IU) significantly reduced time to full sedation to 16.5 min (paired t test, P = 0.024). Reversal was induced with intramuscular atipamezole 0.008 (±0.002) and naltrexone 0.035 (±0.015) mg/kg. Recovery took on average 7 min (3–18 min). The medetomidine/ butorphanol combination provided safe standing sedation for smaller procedures. en_ZA
dc.description.department Production Animal Studies en_ZA
dc.description.embargo 2017-03-31
dc.description.librarian hb2016 en_ZA
dc.description.sponsorship U.S. Fish and Wildlife Service. (African elephant fund AFE 0705), the International Elephant Foundation (Birmingham Zoo, USA).Technology Innovation Agency (Project number TAHC12 - 00042) (Pretoria, South Africa). The German Academic Exchange Service (DAAD, Grant number D/11/44481). en_ZA
dc.description.uri en_ZA
dc.identifier.citation Lüders, I, Tindall, B, Young , D, Van der Horst, G, Botha, S, Luther, I, Maree, L & Bertschinger, HJ 2016, 'Standing sedation with medetomidine and butorphanol in captive African elephants (Loxodonta africana)', Veterinary Journal, vol. 209, pp. 190-192. en_ZA
dc.identifier.issn 1090-0233 (print)
dc.identifier.other 10.1016/j.tvjl.2015.07.014
dc.language.iso en en_ZA
dc.publisher Elsevier en_ZA
dc.rights © 2016 Elsevier Ltd. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Veterinary Journal. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Veterinary Journal, vol. 209, pp. 190-192, 2016. doi : 10.1016/j.tvjl.2015.07.014. en_ZA
dc.subject Elephant bull en_ZA
dc.subject Butorphanol en_ZA
dc.subject Medetomidine en_ZA
dc.subject Hyaluronidase en_ZA
dc.subject African elephant en_ZA
dc.subject Loxodonta africana
dc.title Standing sedation with medetomidine and butorphanol in captive African elephants (Loxodonta africana) en_ZA
dc.type Postprint Article en_ZA

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