Browsing Arthur (Articles) by UP Author "Dreyer, Timothy James"

Browsing Arthur (Articles) by UP Author "Dreyer, Timothy James"

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  • Recombinant sclerostin inhibits bone formation in vitro and in a mouse model of sclerosteosis 
    Dreyer, Timothy; Shah, Mittal; Doyle, Carl; Greenslade, Kevin; Penney, Mark; Creeke, Paul; Kotian, Apoorva; Ke, Hua Zhu; Naidoo, Vinny; Holdsworth, Gill (Elsevier, 2021-07)
    BACKGROUND : Sclerosteosis, a severe autosomal recessive sclerosing skeletal dysplasia characterised by excessive bone formation, is caused by absence of sclerostin, a negative regulator of bone formation that binds LRP5/6 ...