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Please note, we are experiencing high volume submissions; you will receive confirmations of submissions in due course. Data upload (DOI): https://researchdata.up.ac.za/ UPSpace: https://repository.up.ac.za/handle/2263/51914
The influence of dithiosemicarbazone on the immunity of sheep to heartwater
Du Plessis, J.L.; Steyn, P.J.J.; Bigalke, R.D.; Cameron, Colin McKenzie; Gilchrist, Frances M.C.; Morren, A.J.; Verster, Anna J.M.; Verwoerd, Daniel Wynand; Walker, Jane B.
Four out of 9 sheep, immune to heartwater and subsequently treated with gloxazone, showed a
febrile reaction when they were challenged 6 months later, but the same number of untreated controls
also developed this reaction. In a second group of treated immune animals challenged after 9 months,
8 out of 8 showed a febrile reaction, whereas only 3 out of 8 controls reacted. Furthermore, the blood
of one of the 4 sheep that reacted to challenge at 6 months was infective to a susceptible sheep inoculated
with it, whereas that of 4 out of the 8 challenged at 9 months was infective.
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