Four out of 9 sheep, immune to heartwater and subsequently treated with gloxazone, showed a
febrile reaction when they were challenged 6 months later, but the same number of untreated controls
also developed this reaction. In a second group of treated immune animals challenged after 9 months,
8 out of 8 showed a febrile reaction, whereas only 3 out of 8 controls reacted. Furthermore, the blood
of one of the 4 sheep that reacted to challenge at 6 months was infective to a susceptible sheep inoculated
with it, whereas that of 4 out of the 8 challenged at 9 months was infective.
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