Prevention and follow-up in thromboembolic ischemic stroke : do we need to think out of the box?

Show simple item record Swanepoel, A.C. (Albe Carina) Pretorius, Etheresia 2016-02-16T08:13:20Z 2015-12
dc.description.abstract Stroke is one of the most debilitating thrombotic diseases, and world-wide it is estimated that by, 2030, 23 million people will be affected. Except for the impact on the individual families, the world economy is also affected adversely. Although the medical treatment and knowledge of stroke are both increasing and wellresearched, we still do not see a decrease in stroke prevalence. Currently various diagnostic tests are employed to determine the specific type of ischemic stroke as classified by the TOAST criteria. However, these tests are done after the stroke has occurred and therefore only contribute to the unquestionably crucial aspect of treating that particular stroke patient, but it does not improve prevention of future events. Prevention strategies regarding first-time stroke need urgent attention given the alarming present and future incidence of stroke. Therefore, here we discuss the importance of stroke prevention and suggest amore inclusive, perhaps “new” comprehensive approach for pre-stroke screening.Ultrastructural tests, particularly scanning electron microscopy, provide an innovative and novel advance in preventative and individualized patient-centered precision medicine. This precise technique when used in combination with well-established methods, as well as viscoelastic methods like thromboelastography (TEG), as a screening tool to prevent stroke can ultimately alleviate the financial and economical burden of stroke and also improve quality of life. Although we appreciate the fact that this suggestion might be difficult to accept by clinicians, a bold new approach is needed to address this pandemic we call stroke. en_ZA
dc.description.embargo 2016-12-31
dc.description.librarian hb2015 en_ZA
dc.description.sponsorship NRF and MRC of South Africa. en_ZA
dc.description.uri en_ZA
dc.identifier.citation Swanepoel, AC & Pretorius, E 2015, 'Prevention and follow-up in thromboembolic ischemic stroke : do we need to think out of the box?', Thrombosis Research, vol. 136, no. 6, pp. 1067-1073. en_ZA
dc.identifier.issn 0049-3848 (print)
dc.identifier.issn 1879-2472 (online)
dc.identifier.other 10.1016/j.thromres.2015.11.001
dc.language.iso en en_ZA
dc.publisher Elsevier en_ZA
dc.rights © 2015 Elsevier Ltd. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Thrombosis Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Thrombosis Research, vol. 136, no. 6, pp. 1067-1073, 2015. doi : 10.1016/j.thromres.2015.11.001. en_ZA
dc.subject Thromboembolic ischemic stroke en_ZA
dc.subject Scanning electron microscopy en_ZA
dc.subject Comprehensive approach en_ZA
dc.title Prevention and follow-up in thromboembolic ischemic stroke : do we need to think out of the box? en_ZA
dc.type Postprint Article en_ZA

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