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Browsing Workspace (UPSpace) by UP Author "Eloff, Jacobus Nicolaas"

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Anti-inflammatory effects of four psilocybin-containing magic mushroom water extracts in vitro on 15-lipoxygenase activity and on lipopolysaccharide-induced cyclooxygenase-2 and inflammatory cytokines in human U937 macrophage cells

Nkadimeng, Sanah Malomile; Steinmann, Christiaan M.L.; Eloff, Jacobus Nicolaas (Dove Medical Press, 2021-08-05)

Purpose: During a pathological inflammation, macrophages are activated to produce accumulation of inflammatory mediators such as induced-cyclooxygenase-2 (COX-2), 15- lipoxygenase (15-LOX) and pro-inflammatory cytokines. ...
In vitro antiproliferative activity of Ptaeroxylon obliquum leaf extracts, fractions and isolated compounds on several cancer cell lines

Khunoana, Edward Thato; Eloff, Jacobus Nicolaas; Ramadwa, Thanyani Emelton; Nkadimeng, Sanah Malomile; Selepe, Mamoalosi A.; McGaw, Lyndy Joy (MDPI, 2022-10-30)

Several cancers are induced by microbial infections or chronic inflammation. Ptaeroxylon obliquum is traditionally used to treat various infections characterized by inflammation. The in vitro antiproliferative and ...
LC–DAD–MS phenolic characterisation of six invasive plant species in Croatia and determination of their antimicrobial and cytotoxic activity

Poljuha, Danijela; Sladonja, Barbara; Sola, Ivana; Senica, Mateja; Uzelac, Mirela; Veberic, Robert; Hudina, Metka; Famuyide, Ibukun Michael; Eloff, Jacobus Nicolaas; Mikulic-Petkovsek, Maja (MDPI, 2022-02-23)

Invasive plants’ phytochemicals are important for their invasiveness, enabling them to spread in new environments. However, these chemicals could offer many pharmaceutical compounds or active ingredients for herbal ...
A proposal towards a rational classification of the antimicrobial activity of acetone tree leaf extracts in a search for new antimicrobials

Eloff, Jacobus Nicolaas (Georg Thieme Verlag, 2021-08)

Many scientists investigate the potential of finding new antibiotics from plants, leading to more than a thousand publications per year. Many different minimum inhibitory concentrations of extracts have been proposed to ...
Quantitative UPLC-MS/MS analysis of obliquumol from Ptaeroxylon obliquum (Thunb.) Radlk. extracts and biological activities of its semi-synthesised derivative ptaeroxylinol

Ramadwa, Thanyani E.; Selepe, Mamoalosi A.; Sonopo, M.S.; McGaw, Lyndy Joy; Eloff, Jacobus Nicolaas (Elsevier, 2023-05)

Quantification of compounds in plant extracts is rarely conducted to determine variation in concentrations of bioactive constituents. The aim of the study was to develop a method using ultra-performance liquid chromatogr ...
Verification of the folkloric and anecdotal antidiabetic effects of Hypoxis hemerocallidea (Fisch., CA Mey. & Ave-Lall) and isolated, beta-sitosterol using early-stage type II spontaneous diabetic mutant BKS-Lepr(db) mice

Mkolo, Nqobile Monate; Olaokun, O.O.; King, P.H.; Janse van Rensburg, IIse; Eloff, Jacobus Nicolaas; Naidoo, Vinny (BMC, 2022-06-20)

BACKGROUND : Previous studies in our laboratory in ex vivo assays have demonstrated H. hemerocallidea extract as potential antidiabetic agent through increased insulin release from pancreatic beta cells. Thus, for this ...

Now showing items 1-6 of 6

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Browsing Workspace (UPSpace) by UP Author "Eloff, Jacobus Nicolaas"

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