The renin-angiotensin system (RAS) and angiotensin II, in
particular, play a central role and have been implicated in the
spectrum of cardiovascular disease (CVD), beginning with
hypertension, diabetes mellitus, atherosclerosis, myocardial
infarction (MI), strokes and heart failure.
Makkink, Jaco L.; Greeff, O.B.W. (Oppel Bernhardt Wilhelm), 1948-(Health and Medical Publishing Group, 2014-04)
BACKGROUND. Hypertension poses a huge financial risk to any funder/medical aid, including the risk-mitigating strategies provided by the managed
care organisations that are required to manage patients with hypertension. ...
Obesity is the result of genetics which predisposes an individual to obesity and
environmental factors, resulting in excessive weight gain. A well-established linear relationship
exists between hypertension and obesity. ...
Govender, M.M.; Nadar, A.(Institute of Physiology, Czech Academy of Sciences, 2015)
Oxidative stress is an imbalance between free radicals and
antioxidants, and is an important etiological factor in the
development of hypertension. Recent experimental evidence
suggests that subpressor doses of angiotensin ...