Please be advised that the site will be down for maintenance on Sunday, September 1, 2024, from 08:00 to 18:00, and again on Monday, September 2, 2024, from 08:00 to 09:00. We apologize for any inconvenience this may cause.
dc.contributor.author | Du Toit, Eben Francois![]() |
|
dc.contributor.author | Craig, Ian Keith![]() |
|
dc.date.accessioned | 2015-08-25T07:46:40Z | |
dc.date.available | 2015-08-25T07:46:40Z | |
dc.date.issued | 2015-07 | |
dc.description.abstract | Medication is applied to the HIV-infected nodes of high-risk contact networks with the aim of controlling the spread of disease to a predetermined maximum level. This intervention, known as pinning control, is performed both selectively and randomly in the network. These strategies are applied to 300 independent realizations per reference level of incidence on connected undirectional networks without isolated components and varying in size from 100 to 10 000 nodes per network. It is shown that a selective on-off pinning control strategy can control the networks studied with limited steady-state error and, comparing the medians of the doses from both strategies, uses 51.3% less medication than random pinning of all infected nodes. Selective pinning could possibly be used by public health specialists to identify the maximum level of HIV incidence in a population that can be achieved in a constrained funding environment. | en_ZA |
dc.description.librarian | hb2015 | en_ZA |
dc.description.sponsorship | South African Centre for Epidemiological Modelling and Analysis (SACEMA).In part by the National Research Foundation of South Africa (Grant Number 90533). | en_ZA |
dc.description.uri | http://journals.aps.org | en_ZA |
dc.identifier.citation | Du Toit, EF & Craig, IK 2015, 'Selective pinning control of the average disease transmissibility in an HIV contact network', Physical Review E, vol. 92, no. 1, art. # 012810, pp. 1-8 | en_ZA |
dc.identifier.issn | 1539-3755 (print) | |
dc.identifier.issn | 1550-2376 (online) | |
dc.identifier.other | 10.1103/PhysRevE.92.012810 | |
dc.identifier.uri | http://hdl.handle.net/2263/49507 | |
dc.language.iso | en | en_ZA |
dc.publisher | American Physical Society | en_ZA |
dc.rights | © 2015 American Physical Society | en_ZA |
dc.subject | HIV contact network | en_ZA |
dc.subject | Selective pinning control | en_ZA |
dc.subject | Average disease | en_ZA |
dc.subject | Predetermined maximum level | en_ZA |
dc.subject | Human immunodeficiency virus (HIV) | en_ZA |
dc.title | Selective pinning control of the average disease transmissibility in an HIV contact network | en_ZA |
dc.type | Postprint Article | en_ZA |