Several studies have demonstrated the heightened prevalence of colorectal cancer (CRC) among young black men. Most of these
men present with already metastasized CRC. Cancer stem cells (CSCs) play a pivotal role in CRC ...
Prostate cancer (PCa) is the leading cancer in men globally. The association between PCa
and long non-coding RNAs (lncRNAs) has been reported. Aberrantly expressed lncRNAs have been
documented in each of the cancer ...
Selenium is a trace and necessary micronutrient for human, animal, and microbial health. Many researchers have recently been interested in selenium nanoparticles (SeNPs) due to their biocompatibility, bioavailability, and ...
Angiogenesis, the generation of new blood vessels, is one of the hallmarks of cancer. The
growing tumor requires nutrients and oxygen. Recent evidence has shown that tumors release
signals to attract new nerve fibers and ...
Prostate cancer (PCa) continues to be the most diagnosed cancer and the second primary
cause of fatalities in men globally. There is an abundance of scientific evidence suggesting that the
human microbiome, together with ...
Colorectal cancer (CRC) ranks as one of the top causes of cancer mortality worldwide
and its incidence is on the rise, particularly in low-middle-income countries (LMICs). There are
several factors that contribute to the ...
Follicular thyroid carcinoma (FTC) is the second most common cancer of the thyroid
gland, accounting for up to 20% of all primary malignant tumors in iodine-replete areas. The
diagnostic work-up, staging, risk stratification, ...
BACKGROUND : Breast cancer is the most common type of cancer in women, and vast research is being conducted throughout the world for the treatment of this malignancy by natural products using various computational approaches. ...
About 15% of all human cancers have a viral etiology. Although progress has been made,
understanding the viral oncogenesis and associated molecular mechanisms remain complex. The
discovery of cellular miRNAs has led to ...
Basera, Afra; Hull, Rodney; Demetriou, Demetra Danielle; Bates, David Owen; Kaufmann, Andreas Martin; Dlamini, Zodwa; Marima, Rahaba(MDPI, 2022-09-16)
Cervical cancer (CC) is the primary cause of female cancer fatalities in low-middle-income
countries (LMICs). Persistent infections from the human papillomavirus (HPV) can result in cervical
cancer. However, numerous ...
Mlambo, Musikavanhu Roy(University of Pretoria, 2023)
Breast cancer in women is the most prevalent cancer in both developed and less developed countries, with an incidence of about 2.3 million new cases diagnosed in 2020, which is about 25% of all cancers in women. Several ...
Precision medicine is the personalization of medicine to suit a specific group of people or even an individual patient, based on genetic or molecular profiling. This can be done using genomic, transcriptomic, epigenomic ...
Gastric cancer (GC) is one of the major causes of cancer deaths worldwide. The disease is seldomly detected early and this limits treatment options. Because of its heterogeneous and complex nature, the disease remains ...
Angiogenesis is one of the hallmarks of cancer, and the establishment of new blood vessels
is vital to allow for a tumour to grow beyond 1–2 mm in size. The angiogenic switch is the term
given to the point where the ...
MicroRNAs (miRNA) are small non-coding RNAs that are 20–23 nucleotides in length,
functioning as regulators of oncogenes or tumor suppressor genes. They are molecular modulators
that regulate gene expression by suppressing ...
Mbeje, Mandisa Pearl(University of Pretoria, 2023)
Prostate cancer (PCa) incidence rates continue to rise with an estimation of 375 000 deaths and 1.4 million new cases in the year 2020. It has become the second most commonly occurring cancer and the fifth most frequent ...
Prostate cancer (PCa) is a leading cause of mortality in men of African origin. While men of African descent in high-income countries (HICs) demonstrate poor prognosis compared to their European counterparts, African men ...
Worldwide, oesophageal cancer is the sixth leading cause of deaths related to cancer and
represents a major health concern. Sub-Saharan Africa is one of the regions of the world with the
highest incidence and mortality ...