S1 Text. Supporting bibliography.
S1 Table. Estimates by country of rabies deaths, exposures, PEP use, prevented deaths, dog
vaccination coverage, probability that a dog is rabid (RP), of bite victims receiving PEP
(PP), DALYs, costs and 95% confidence intervals of estimates. Clusters to which countries
are assigned are shown and inputs used for estimating parameters including the human development
index and whetehr a country s rabies-free or endemic (RISK). Estimates of years of life
lost (YLL) and DALYs (due to rabies and to adverse events from the use of nerve tissue vaccines) are shown under different assumptions (estimates under the assumption of no time
discounting or age-weighting should be directly comparable to the 2010 Global Burden of Disease
study).
S1 Fig. Division of costs associated with rabies, prevention and control across sectors by
cluster. Inset shows proportional expenditure in different clusters. Full details of countries by
cluster are given in S1 Table. Asia 4 comprises: Philippines, Sri Lanka, Thailand (High PEP
use); Asia 3 comprises Bhutan, Nepal, Bangladesh, Pakistan (Himalayan region); Asia 2 comprises
Cambodia, Myanmar, Laos, Vietnam and Democratic People’s Republic of Korea;
SADC comprises countries in the Southern African Development Community, Eurasia comprises
Afghanistan, Kazakhstan, Kyrgyzstan, Mongolia, the Russian Federation, Turkmenistan,
Tajikistan, and Uzbekistan.
S1 Dataset. Model code and input data files including references, rationale and detail of
Delphi process. The code folder contains seven R scripts: burden_model.R runs the model
using data compiled in burden_1.R, after estimating parameters using: FitCovInc.R, FitPP.R,
and creating Fig 2 (RabiesBurdenFig2.R). The script burden_results.R summarizes findings
using the output of burden_model.R and burden_sensitivity.R runs the sensitivity analyses. The
data folder contains 12 csv files called by the R code for the analyses, and one excel file (Vet.
xlsx) with additional details about the data sources in vcountry2.csv and vcluster2.csv and with
Delphi process estimates for dog vaccination coverage. Data sources are detailed in the relevant
data sources and the details of the sources of data used in the analysis are in the supporting bibliography,
S1 text.