Nolte, Elsie Magdalena; Joubert, Annie M.; Lakier, Roy; Van Rensburg, Ado; Mercier, Anne Elisabeth(MDPI Publishing, 2018)
Following exposure of cells to gamma-radiation, a cascade of intracellular consequences
may be observed in a semitemporal manner. This includes deoxyribonucleic acid (DNA) damage and
reactive oxygen species (ROS) ...
Helena, Jolene Michelle; Joubert, Anna Margaretha; Mabeta, Peaceful Lucy; Coetzee, Magdalena; Lakier, Roy; Mercier, Anne Elisabeth(MDPI, 2021-08-17)
2-Ethyl-3-O-sulfamoyl-estra-1,3,5(10)16-tetraene (ESE-16) is an in silico-designed estradiol
analogue which has improved the parent compound’s efficacy in anti-cancer studies. In this proofof-
concept study, the potential ...
