Orthobunyavirus antibodies among humans in selected parts of the Rift Valley and northeastern Kenya
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Date
Authors
Odhiambo, Collins
Venter, Marietjie
Swanepoel, Robert
Sang, Rosemary
Journal Title
Journal ISSN
Volume Title
Publisher
Mary Ann Liebert
Abstract
Ngari, Bunyamwera, Ilesha, and Germiston viruses are among the mosquito-borne human pathogens in the
Orthobunyavirus genus, family Bunyaviridae, associated with febrile illness. Although the four orthobunyaviruses
have been isolated from mosquito and/or tick vectors sampled from different geographic regions in
Kenya, little is known of human exposure in such areas. We conducted a serologic investigation to determine
whether orthobunyaviruses commonly infect humans in Kenya. Orthobunyavirus-specific antibodies were detected
by plaque reduction neutralization tests in 89 (25.8%) of 345 persons tested. Multivariable analysis
revealed age and residence in northeastern Kenya as risk factors. Implementation of acute febrile illness
surveillance in northeastern Kenya will help to detect such infections.
Description
Keywords
Orthobunyavirus, Bunyaviridae, Arboviruses, Kenya
Sustainable Development Goals
Citation
Odhiambo, C, Venter, M, Swanepoel, R & Sang, R 2015, 'Orthobunyavirus antibodies among humans in selected parts of the rift valley and northeastern Kenya', Vector-Borne and Zoonotic Diseases, vol. 15, no. 5, pp. 329-332.