Isolation and characterization of and some observations on poisoning by bufadienolides from Cotyledon orbiculata L. var. orbiculata
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| dc.contributor.author | Anderson, L.A.P.
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| dc.contributor.author | Schultz, R.A. (Rowena Anitra)
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| dc.contributor.author | Kellerman, T. Stephanus
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| dc.contributor.author | Kotze, S.M.
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| dc.contributor.author | Erasmus, G.L.
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| dc.contributor.author | Labuschagne, Leonie
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| dc.contributor.editor | Bigalke, R.D. | |
| dc.contributor.upauthor | Prozesky, Leon | |
| dc.date.accessioned | 2015-03-31T13:03:03Z | |
| dc.date.available | 2015-03-31T13:03:03Z | |
| dc.date.created | 2014 | |
| dc.date.issued | 1985 | |
| dc.description | The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. | en_ZA |
| dc.description.abstract | The approximate LD₅₀ and cumulative effect of 4 bufadienolides, isolated from Cotyledon orbiculata, were determined in guinea-pigs. Two of the bufadienolides proved to be mildly cumulative. One of the mildly cumulative bufadienolides induced subacute intoxication with some signs of krimpsiekte when injected intravenously into a sheep over 13 days. In the sheep, the paralysis was accompanied by signs of malaise, such as electrocardiographic changes and ruminal stasis. | en_ZA |
| dc.identifier.citation | Anderson, LAP, Schultz, RA, Kellerman, TS, Kotze, SM, Prozesky, L, Erasmus, GL & Labuschagne, L 1985, 'Isolation and characterization of and some observations on poisoning by bufadienolides from Cotyledon orbiculata L. var. orbiculata’, Onderstepoort Journal of Veterinary Research, vol. 52, no. 1, pp. 21-24. | en_ZA |
| dc.identifier.issn | 0330-2465 | |
| dc.identifier.uri | http://hdl.handle.net/2263/44225 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | Published by the Government Printer, Pretoria. | en_ZA |
| dc.rights | ©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital). | en_ZA |
| dc.subject | Veterinary medicine | en_ZA |
| dc.subject.lcsh | Veterinary medicine | |
| dc.title | Isolation and characterization of and some observations on poisoning by bufadienolides from Cotyledon orbiculata L. var. orbiculata | en_ZA |
| dc.type | Article | en_ZA |
