Atypical erythrocytes and platelets in a patient with a pro-thrombin mutation

Show simple item record Pretorius, Etheresia Vermeulen, Natasha Bester, Janette 2015-03-26T10:06:27Z 2015-03-26T10:06:27Z 2014-06
dc.description.abstract Prothrombin mutation G20210A, anti-phospholipid syndrome as well as iron overload has previously been shown to cause thrombotic events. The main reason for this is the involvement of these anomalies in causing hypercoagulability of the coagulation system, which frequently leads to venous and arterial thrombotic events. We report the case of a 37-year-old white female with prothrombin mutation G20210A, anti-phospholipid syndrome, as well as an increased serum ferritin level, who experienced two transient ischemic attacks and suffers from regular amaurosis fugax. We present an ultrastructural depiction of erythrocytes, platelets, and the fibrin network, to explain the clinical manifestations of the thrombotic state seen in this patient. en_ZA
dc.description.embargo 2015-06-30 en_ZA
dc.description.librarian hb2015 en_ZA
dc.description.uri en_ZA
dc.identifier.citation Pretorius, E, Vermeulen, N & Bester, J 2014, 'Atypical erythrocytes and platelets in a patient with a pro-thrombin mutation', Platelets, vol. 25, no. 6, pp. 461-462. en_ZA
dc.identifier.issn 0953-7104 (print)
dc.identifier.issn 1369-1635 (online)
dc.identifier.other 10.3109/09537104.2013.830709
dc.language.iso en en_ZA
dc.publisher Informa Healthcare en_ZA
dc.rights © Informa Healthcare. This is an electronic version of an article published in Inhalation Toxicology, vol. 25, no. 6, pp. 461-462, 2014. doi : 10.3109/09537104.2013.830709. Inhalation Toxicology is available online at : is an open-access article distributed under the terms of the CC-BY-NC-ND 3.0 en_ZA
dc.subject Iron overload en_ZA
dc.subject Platelets en_ZA
dc.subject Pro-thrombin mutation en_ZA
dc.subject Red blood cells (RBCs) en_ZA
dc.title Atypical erythrocytes and platelets in a patient with a pro-thrombin mutation en_ZA
dc.type Article en_ZA

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