The pathogenesis of heartwater

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dc.contributor.author Heartwater : Past, Present and Future. Workshop (1986 : Kruger National Park, South Africa)
dc.contributor.author Du Plessis, J.L.
dc.contributor.author Malan, Letitia
dc.contributor.author Kowalski, Z.E.
dc.contributor.editor Bigalke, R.D.
dc.date.accessioned 2014-11-19T10:19:00Z
dc.date.available 2014-11-19T10:19:00Z
dc.date.created 2014
dc.date.issued 1987
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_US
dc.description.abstract Hypotheses on the pathogenesis of heartwater, which have been published so far, are briefly reviewed. Attempts were made at counteracting the effects of vaso-active substances released by mast cells by treating mice infected with Cowdria ruminantium with antagonists to histamin and serotonin on one hand, and with mast cell stabilizers on the other, but were not successful. Preliminary findings suggest that a hypersensitive type of reaction, triggered by the release of pharmacologically active substances, may possibly be basic to the pathogenesis of heartwater. Complement, and the products of arachidonic acid metabolism, possibly play a role in the release of the vaso-active substances. en_US
dc.description.librarian lmchunu2014 en_US
dc.description.librarian mn2014
dc.identifier.citation Du Plessis, JL, Malan, L & Kowalski, ZE 1987, 'The pathogenesis of heartwater’, Onderstepoort Journal of Veterinary Research, vol. 54, no. 3, pp. 313-318. en_US
dc.identifier.issn 0330-2465
dc.identifier.uri http://hdl.handle.net/2263/42665
dc.language.iso en en_US
dc.publisher Published by the Government Printer, Pretoria. en_US
dc.rights ©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital). en_US
dc.subject Veterinary medicine en_US
dc.subject.lcsh Veterinary medicine -- South Africa
dc.subject.lcsh Heartwater -- South Africa en
dc.title The pathogenesis of heartwater en_US
dc.title.alternative Heartwater : past, present and future : proceedings of a workshop held at Berg en Dal, Kruger National Park, on 8-16 September 1986
dc.type Article en_US


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