Mathematical modeling of HIV dynamics after antiretroviral therapy initiation : a clinical research study
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Date
Authors
Rivadeneira, Pablo S.
Moog, Claude H.
Stan, Guy-Bart
Costanza, Vicente
Brunet, Cécile
Raffi, Francois
Ferré, Virginie
Mhawej, Marie-José
Biafore, Federico
Ouattara, Djomangan A
Journal Title
Journal ISSN
Volume Title
Publisher
Mary Ann Liebert
Abstract
Immunological failure is identified from the estimation
of certain parameters of a mathematical model
of HIV infection dynamics. This identification is supported
by clinical research results from an original clinical trial.
Standard clinical data were collected from infected patients
starting highly active antiretroviral therapy (HAART) after
just 1 month of therapy initiation and were used to carry out
the model identification. The early diagnosis is shown to be
consistent with patient monitoring after 6 months.
Description
Keywords
Mathematical modeling, HIV dynamics, Antiretroviral therapy initiation, Human immunodeficiency virus (HIV), Highly active antiretroviral therapy (HAART)
Sustainable Development Goals
Citation
Rivadeneira, PS, Moog, CH, Stan, G-B, Costanza, V, Brunet, C, Raffi, F, Ferré, V, Mhawej, M-J, Biafore, F, Ouattara, DA, Ernst, D, Fonteneau, R & Xia, X 2014, 'Mathematical modeling of HIV dynamics after antiretroviral therapy initiation :aA clinical research study', AIDS Research and Human Retroviruses, vol. 30, no. 9, pp. 831-834.