Experience in South Africa of combining bioanalysis and instrumental analysis of PCDD/Fs

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Authors

De Vos, Jayne
Quinn, Laura
Roos, Claudine
Pieters, Rialet
Gorst-Allman, Peter
Rohwer, Egmont Richard
Giesy, John P.
Bouwman, Henk

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Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

We outline the experiences and the challenges of optimizing two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GCxGC-TOF-MS) in conjunction with the H4IIE-luc bioassay for analyzing polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in the South African context. Investigating such alternative analytical methods can assist countries with developing economies to meet their obligations under the Stockholm Convention.

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Keywords

Bioanalysis, H4IIE-luc bioassay, Persistent organic pollutant (POP), Polychlorinated dibenzo-p-dioxin (PCDD), Polychlorinated dibenzofuran (PCDF), Soil, Stockholm convention, Time-of-flight mass spectrometry (TOF-MS), Two-dimensional gas chromatography (GCxGC), South Africa (SA)

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Citation

Vos JD, Quinn L, Roos C, Pieters R, Gorst-Allman P, Rohwer ER, Giesy JP & Bouwman H 2013, 'Experience in South Africa of combining bioanalysis and instrumental analysis of PCDD/Fs', TrAC Trends in Analytical Chemistry, vol. 46, no. 189-197.