Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems

Show simple item record Arnold, Kathryn E. Boxall, Alistair B.A. Brown, A. Ross Cuthbert, Richard Gaw, Sally Hutchinson, Thomas H. Jobling, Susan Madden, Judith C. Metcalfe, Chis D. Naidoo, Vinny Shore, Richard F. Smits, Judit E. Taggart, Mark A. Thompson, Helen M. 2014-10-10T05:15:44Z 2014-10-10T05:15:44Z 2013
dc.description.abstract The use of human and veterinary pharmaceuticals is increasing. Over the past decade, there has been a proliferation of research into potential environmental impacts of pharmaceuticals in the environment. A Royal Society-supported seminar brought together experts from diverse scientific fields to discuss the risks posed by pharmaceuticals to wildlife. Recent analytical advances have revealed that pharmaceuticals are entering habitats via water, sewage, manure and animal carcases, and dispersing through food chains. Pharmaceuticals are designed to alter physiology at low doses and so can be particularly potent contaminants. The near extinction of Asian vultures following exposure to diclofenac is the key example where exposure to a pharmaceutical caused a population-level impact on non-target wildlife. However, more subtle changes to behaviour and physiology are rarely studied and poorly understood. Grand challenges for the future includedevelopingmore realistic exposure assessments forwildlife, assessingthe impacts ofmixtures ofpharmaceuticals in combination with otherenvironmental stressors andestimating the risks frompharmaceutical manufacturing and usage in developing countries. We concluded that an integration of diverse approaches is required to predict ‘unexpected’ risks; specifically, ecologically relevant, often long-termand non-lethal, consequences of pharmaceuticals in the environment for wildlife and ecosystems. en_US
dc.description.librarian hb2014 en_US
dc.description.sponsorship Research Fellow International Scientific Seminar grant from the Royal Society en_US
dc.description.uri en_US
dc.identifier.citation Arnold, KE, Boxall, ABA, Brown, AR, Cuthbert, RJ, Gaw, S, Hutchinson, TH, Jobling, S, Madden, JC, Metcalfe, CD, Naidoo, V, Shore, RF, Smits, JE, Taggart, MA & Thompson, HM 2013, 'Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems', Biology Letters, vol. 9, no. 4, art. #20130492, pp. 1-4. en_US
dc.identifier.issn 1744-9561 (print)
dc.identifier.issn 1744-957X (online)
dc.identifier.other 10.1098/rsbl.2013.0492
dc.identifier.other 8621439700
dc.identifier.other A-1508-2008 
dc.language.iso en en_US
dc.publisher The Royal Society en_US
dc.rights © 2013 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License en_US
dc.subject Wildlife en_US
dc.subject Endocrine-disrupting chemicals en_US
dc.subject Non-steroidal anti-inflammatory drugs en_US
dc.subject Vultures en_US
dc.subject Risk prediction en_US
dc.subject Bioindicators en_US
dc.title Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems en_US
dc.type Article en_US

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