Three proposed new bacteriophage genera of staphylococcal phages : "3alikevirus", "77likevirus" and "Phietalikevirus"

Show simple item record Gutiérrez, Diana Adriaenssens, Evelien M. Martínez, Beatriz Rodríguez, Ana Lavigne, Rob Kropinski, Andrew M. García, Pilar 2014-10-02T12:03:32Z 2014-10-02T12:03:32Z 2014-02
dc.description.abstract To date, most members of the Siphoviridae family of bacteriophages remain unclassified, including the 46 staphylococcal phages for which the complete genome sequences have been deposited in public databases. Comparative nucleotide and protein sequence analysis, in addition to available data on phage morphology, allowed us to propose three new phage genera within the family Siphoviridae: ‘‘3alikevirus’’, ‘‘77likevirus’’ and ‘‘Phietalikevirus’’, which include related phages infecting Staphylococcus aureus and Staphylococcus epidermidis. However, six phages infecting S. aureus, Staphylococcus pasteuri, Staphylococcus hominis and Staphylococcus capitis strains remain to be classified (orphan phages). Overall, the former phages share morphological features and genome organization. The three groups have conserved domains containing peptidoglycan hydrolytic activities clearly identified as part of tape measure proteins (‘‘3alikevirus’’ and ‘‘77likevirus’’) or as individual virionassociated proteins (‘‘Phietalikevirus’’). In addition, bacteriophages belonging to the genus ‘‘3alikevirus’’ share closely related DNA-processing and packaging proteins, while bacteriophages included in the genus ‘‘Phietalikevirus’’ encode specific tail proteins for host interaction. These properties are considered distinctive for these genera. Orphan phages seem to have a more divergent organization, but they share some properties with members of these proposed genera. en_US
dc.description.embargo 2015-02-26
dc.description.librarian hb2014 en_US
dc.description.sponsorship AGL2012-40194-C02-01 (Ministry of Science and Innovation, Spain)and bacteriophage network FAGOMA. Ministry of Science and Innovation, Spain. FWO Vlaanderen–funded ‘‘Phagebiotics’’ research community (WO.022.09) en_US
dc.description.uri en_US
dc.identifier.citation Gutiérrez, D, Adriaenssens, EM, Martínez, B, Rodríguez, A, Lavigne, R, Kropinski, AM & García, P 2014, 'Three proposed new bacteriophage genera of staphylococcal phages : "3alikevirus", "77likevirus" and "Phietalikevirus"', Archives of Virology, vol. 159, no. 2, pp. 389-398. en_US
dc.identifier.issn 0304-8608 (print)
dc.identifier.issn 1432-8798 (online)
dc.identifier.other 10.1007/s00705-013-1833-1
dc.language.iso en en_US
dc.publisher Springer en_US
dc.rights © Springer-Verlag Wien 2013. The original publication is available at : en_US
dc.subject Remain unclassified en_US
dc.subject Family Siphoviridae en_US
dc.subject New bacteriophage genera en_US
dc.subject ‘‘3alikevirus’’ en_US
dc.subject ‘‘77likevirus’’ en_US
dc.subject ‘‘Phietalikevirus’’ en_US
dc.title Three proposed new bacteriophage genera of staphylococcal phages : "3alikevirus", "77likevirus" and "Phietalikevirus" en_US
dc.type Postprint Article en_US

Files in this item

This item appears in the following Collection(s)

Show simple item record