dc.contributor.author |
Spickett, Arthur M.
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dc.contributor.author |
Burger, D.B.
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dc.contributor.author |
Crause, J.C.
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dc.contributor.author |
Roux, Elizabeth M.
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dc.contributor.editor |
Verwoerd, Daniel Wynand |
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dc.contributor.upauthor |
Neitz, Albert Walter Herman
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dc.date.accessioned |
2014-08-19T06:17:59Z |
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dc.date.available |
2014-08-19T06:17:59Z |
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dc.date.created |
2013 |
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dc.date.issued |
1991 |
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dc.description |
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. |
en |
dc.description.abstract |
Although of low morbidity, sweating sickness is readily induced in calves by infestation with positive Hyalomma truncatum adult ticks. This epitheliotrophic disease has no specific cure except by the administration of hyperimmune serum obtained from animals which have recovered and are subsequently immune to the disease. Treatment with hyperimmune serum, however, has associated problems of donor availability, possible serum contamination and i.v. administration of a relatively large volume. This paper compares the treatment and cure of sweating sickness using unrefined hyperimmune serum and that of an experimental suspension. The latter proved relatively inefficient probably due to a low concentration of effective immunoglobulins. Immunoblot analyses of the sera of affected animals, using tick salivary glands as antigen during the course of the trial revealed 4 tick salivary gland proteins with molecular masses of between 27-33 kDa. These are proposed as being associated with sweating sickness immunodominance. |
en |
dc.description.librarian |
mn2014 |
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dc.identifier.citation |
Spickett, AM, Burger, DB, Crause, JC, Roux, EM & Neitz, AWH 1991, 'Sweating sickness : relative curative effect of hyperimmune serum and a precipitated immunoglobulin suspension and immunoblot identifiation of proposed immunodominant tick salivary gland proteins’, Onderstepoort Journal of Veterinary Research, vol. 58, no. 3, pp. 223-226. |
en |
dc.identifier.issn |
0330-2465 |
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dc.identifier.uri |
http://hdl.handle.net/2263/41430 |
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dc.language.iso |
en |
en |
dc.publisher |
Published by the Agricultural Research Council, Onderstepoort Veterinary Institute. |
en |
dc.rights |
©South Africa. Dept. of Agricultural Technical Services. ©University of Pretoria. Dept. of Library Services (digital). |
en |
dc.subject |
Veterinary medicine |
en |
dc.subject.lcsh |
Veterinary medicine -- South Africa |
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dc.title |
Sweating sickness : relative curative effect of hyperimmune serum and a precipitated immunoglobulin suspension and immunoblot identifiation of proposed immunodominant tick salivary gland proteins |
en |
dc.type |
Article |
en |