Recombinant rabies vaccines : efficacy assessment in free-ranging animals

Show simple item record Rupprecht, Charles Edward Hanlon, C.A. Niezgoda, M. Buchanan, J.R. Diehl, D. Koprowski, H. Rabies in Southern and Eastern Africa. Workshop. (1993, Pretoria, South Africa)
dc.contributor.editor Verwoerd, Daniel Wynand 2014-08-15T08:17:49Z 2014-08-15T08:17:49Z 2013 1993
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en
dc.description.abstract With the advancement of recombinant DNA techniques, a number of potent biologicals are available for the oral vaccination of free-ranging animals. Once oral immunogenicity and vaccine safety have been demonstrated, efficacy then becomes of paramount importance. Classical assessment of efficacy is conducted under carefully controlled laboratory conditions, whereas efficacy of oral wildlife rabies vaccination programs, to date, have been assessed by the lack (or occurrence) of field cases of rabies in a vaccinated area. This communication describes an intermediate vaccine efficacy strategy in which self-vaccinated, free-ranging animals from a study site were captured seven months after vaccine-laden bait distribution for laboratory rabies challenge. This technique is specifically reviewed in the context of available recombinant products for the consideration of extension towards dog rabies control. en
dc.description.librarian mn2014
dc.identifier.citation Rupprecht, CE, Hanlon, CA, Niezgoda, M, Buchanan, JR, Diehl, D & Koprowski, H 1993, 'Recombinant rabies vaccines : efficacy assessment in free-ranging animals’, Onderstepoort Journal of Veterinary Research, vol. 60, no. 4, pp. 463-468. en
dc.identifier.issn 0330-2465
dc.language.iso en en
dc.publisher Published by the Agricultural Research Council, Onderstepoort Veterinary Institute en
dc.rights © ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital). en
dc.subject Veterinary medicine en
dc.subject Rabies in southern and eastern Africa. Proceedings of a workshop held at the Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa, 3-5 May 1993 en
dc.subject.lcsh Veterinary medicine -- South Africa
dc.subject.lcsh Rabies in animals
dc.title Recombinant rabies vaccines : efficacy assessment in free-ranging animals en
dc.type Article en

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