Effect of calcium and cholecalciferol supplementation on several parameters of calcium status in plasma and urine of captive Asian (Elephas maximus) and African elephants (Loxodonta Africana)

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dc.contributor.author Van Sonsbeek, Gerda R.
dc.contributor.author Van der Kolk, Johannes H.
dc.contributor.author Van Leeuwen, Johannes P.T.M.
dc.contributor.author Everts, Hendrik
dc.contributor.author Marais, Johan
dc.contributor.author Schaftenaar, Willem
dc.date.accessioned 2014-07-16T06:14:03Z
dc.date.available 2014-07-16T06:14:03Z
dc.date.issued 2013-09
dc.description.abstract The aim of the current study was to assess the effect of oral calcium and cholecalciferol supplementation on several parameters of calcium status in plasma and urine of captive Asian (Elephas maximus; n = 10) and African elephants (Loxodonta africana; n = 6) and to detect potential species differences. Calcium and cholecalciferol supplementation were investigated in a feeding trial using a crossover design consisting of five periods of 28 days each in summer. From days 28–56 (period 2), elephants were fed the Ca-supplemented diet and from days 84–112, elephants were fed the cholecalciferol-supplemented diet (period 4). The control diet was fed during the other periods and was based on their regular ration, and the study was repeated similarly during winter. Periods 1, 3, and 5 were regarded as washout periods. This study revealed species-specific differences with reference to calcium and cholecalciferol supplementation. Asian elephants showed a significant increase in mean plasma total calcium concentration following calcium supplementation during summer, suggesting summerassociated subclinical hypocalcemia in Western Europe. During winter, no effect was seen after oral calcium supplementation, but a significant increase was seen both in mean plasma, total, and ionized calcium concentrations after cholecalciferol supplementation in Asian elephants. In contrast, evidence of subclinical hypocalcemia could be demonstrated neither in summer nor in winter in African elephants, although 28 days of cholecalciferol supplementation during winter reversed the decrease in plasma 1,25(OH)2-cholecalciferol and was followed by a significant increase in mean plasma total calcium concentration. Preliminary findings indicate that the advisable permanent daily intake for calcium in Asian elephants and cholecalciferol in both elephant species at least during winter might be higher than current guidelines. It is strongly recommended to monitor blood calcium concentrations and, if available, blood parathyroid hormone levels to adjust the nutritional supplementation for each individual elephant. en_US
dc.description.librarian am2014 en_US
dc.description.uri http://zoowildlifejournal.com/ en_US
dc.identifier.citation Van Sonsbeek, GR, Van der Kolk, JH, Van Leeuwen, JPTM, Everts, H, Marais, J & Schaftenaar, W 2013, 'Effect of calcium and cholecalciferol supplementation on several parameters of calcium status in plasma and urine of captive Asian (Elephas maximus) and African elephants (Loxodonta Africana)', Journal of Zoo and Wildlife Medicine, vol. 44, no. 3, pp. 529-540. en_US
dc.identifier.issn 1042-7260 (print)
dc.identifier.issn 1937-2825 (online)
dc.identifier.uri http://hdl.handle.net/2263/40806
dc.language.iso en en_US
dc.publisher American Association of Zoo Veterinarians en_US
dc.rights Copyright 2013 by American Association of Zoo Veterinarians en_US
dc.subject Calcium en_US
dc.subject Cholecalciferol en_US
dc.subject African elephant en_US
dc.subject Asian elephant en_US
dc.subject Loxodonta africana
dc.subject Elephas maximus
dc.title Effect of calcium and cholecalciferol supplementation on several parameters of calcium status in plasma and urine of captive Asian (Elephas maximus) and African elephants (Loxodonta Africana) en_US
dc.type Article en_US


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