Biomarkers in canine parvovirus enteritis

Show simple item record Schoeman, Johan P. Goddard, Amelia Leisewitz, Andrew L. 2014-06-06T07:16:06Z 2013
dc.description.abstract Canine parvovirus (CPV) enteritis has, since its emergence in 1978, remained a common and important cause of morbidity and mortality in young dogs. The continued incidence of parvoviral enteritis is partly due to the virus’ capability to evolve into more virulent and resistant variants with significant local gastrointestinal and systemic inflammatory sequelae. This paper reviews current knowledge on historical-, signalment-, and clinical factors as well as several haematological-, biochemical- and endocrine parameters that can be used as diagnostic and prognostic biomarkers in CPV enteritis. These factors include season of presentation, purebred nature, bodyweight, vomiting, leukopaenia, lymphopaenia, thrombocytopaenia, hypercoagulability, hypercortisolaemia, hypothyroxinaemia, hypoalbuminaemia, elevated C-reactive protein and tumour necrosis factor, hypocholesterolaemia and hypocitrullinaemia. Factors contributing to the manifestations of CPV infection are multiple with elements of host, pathogen, secondary infections, underlying stressors and environment affecting severity and outcome. The availability of several prognosticators has made identification of patients at high risk of death and their subsequent targeted management more rewarding. en
dc.description.librarian hj2014 en
dc.description.librarian mn2014
dc.description.uri en
dc.identifier.citation J P Schoeman , A Goddard & A L Leisewitz (2013) Biomarkers in canine parvovirus enteritis, New Zealand Veterinary Journal, 61:4, 217-222, DOI: 10.1080/00480169.2013.776451. en
dc.identifier.issn 0048-0169 (print)
dc.identifier.issn 1176-0710 (online)
dc.identifier.other 10.1080/00480169.2013.776451
dc.identifier.other 6701514975
dc.identifier.other 7005814117
dc.identifier.other C-3865-2012
dc.identifier.other J-6765-2013
dc.language.iso en en
dc.publisher Taylor & Francis en
dc.rights © 2013 New Zealand Veterinary Association. This is an electronic version of an article published in New Zealand Veterinary Journal, 61:4, 217-222, DOI: 10.1080/00480169.2013.776451. New Zealand Veterinary Journal is available online at : en
dc.subject Canine parvovirus (CPV) en
dc.subject Mortality en
dc.subject Leukopaenia en
dc.subject Canine viral disease en
dc.subject Hypercortisolaemia en
dc.subject Hypothyroxinaemia en
dc.subject Hypocholesterolaemia en
dc.subject Canine diagnostics en
dc.subject Canine prognostics en
dc.subject.lcsh Canine parvovirus infections en
dc.subject.lcsh Dogs -- Virus diseases en
dc.title Biomarkers in canine parvovirus enteritis en
dc.type Postprint Article en

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