dc.contributor.author |
Abbavaram, Babul Reddy A.
|
|
dc.contributor.author |
Reddyvari, Hymavathi R.V.
|
|
dc.date.accessioned |
2014-05-29T10:25:01Z |
|
dc.date.available |
2014-05-29T10:25:01Z |
|
dc.date.issued |
2013 |
|
dc.description.abstract |
A convenient synthesis of bifunctional sulfonamide-amide derivatives was reported. Amide coupling of 4-methyl
benzoic acid 1 followed by reaction with chlorosulfonic acid produce ethyl-4-(3-(chlorosulfonyl)-4-methylbenzoyl)piperazine-
1-carboxylate 4. The resulted compound on further treatment with various anilines produces the title sulfonamide-amide derivatives
5a−n. The configurations of these compounds were established by elemental analysis, IR, 1H NMR, mass spectra, and
by their preparation from the corresponding 4-methyl benzoic acid 1 and chlorosulfonic acid. All these new compounds demonstrate
significant in vitro antibacterial and antifungal activities against all bacterial and fungal strains. |
en_US |
dc.description.librarian |
am2014 |
en_US |
dc.description.sponsorship |
Korean Chemical Society |
en_US |
dc.description.uri |
http://journal.kcsnet.or.kr/ |
en_US |
dc.identifier.citation |
Abbavaram, BRA & Reddyvari, HRV 2013, 'Synthesis, characterization and antimicrobial activity of bifunctional sulfonamide-amide derivatives', Journal of the Korean Chemical Society, vol. 57, no. 6, pp. 731-737. |
en_US |
dc.identifier.issn |
1017-2548 (print) |
|
dc.identifier.issn |
2234-8530 (online) |
|
dc.identifier.other |
10.5012/jkcs.2013.57.6.731 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/39938 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
Korean Chemical Society |
en_US |
dc.rights |
Korean Chemical Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution License |
en_US |
dc.subject |
Sulfonamide-amide |
en_US |
dc.subject |
4-Methyl benzoic acid |
en_US |
dc.subject |
Chlorosulfonic |
en_US |
dc.subject |
Antibacterial and antifungal activities |
en_US |
dc.title |
Synthesis, characterization and antimicrobial activity of bifunctional sulfonamide-amide derivatives |
en_US |
dc.type |
Article |
en_US |