Malaria continues to be a major infectious disease with 229 million cases reported in 2019 of which 94% occurred in the African region. Problems such as poor aqueous solubility, instability, toxicity and drug resistance ...

Tuberculosis (TB) is a highly contagious chronic pulmonary disease caused by Mycobacterium tuberculosis (M.tb). Early detection of this deadly disease using a simple and effective method at the point of care is not yet ...

Tautomeric and anionic forms of nucleic acids are potentially involved in mutations and replication and translational errors; however, research into the chemistry of deprotonated nucleobases is limited. This research focused ...

The current global tuberculosis epidemic has shown the need to urgently replace the aged anti-TB armamentarium. The search for a fast, accurate and reliable diagnosis of active TB has emerged as the spearhead in efforts ...

Malaria remains a global burden, specifically affecting developing countries in sub-Saharan Africa, East Asia and Oceania. To address the high mortality rates associated with severe malaria, researchers at the Council of ...