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Browsing Natural and Agricultural Sciences by UP Author "Nell, Margo Judith"

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Binding pose analysis of hydroxyethylamine based β-secretase inhibitors and application thereof to the design and synthesis of novel indeno[1,2-b]indole based inhibitors

Van der Westhuizen, Carl Johan; Van Greunen, D.G. (Divan); Cordier, Werner; Nell, Margo Judith; Steenkamp, Vanessa; Stander, Andre; Panayides, Jenny-Lee; Riley, Darren L. (ARKAT, 2020-04)

β-Secretase (BACE1) is recognised as a target for the treatment of Alzheimer’s disease, and transition-state isosteres such as hydroxyethylamines have shown promise when incorporated into BACE1 inhibitors. A computational ...
Cannabidiol-mediated green synthesis, characterization, and cytotoxicity of metal nanoparticles in human keratinocyte cells

Josiah, Andrea Jess; Pillai, Sreejarani Kesavan; Cordier, Werner; Nell, Margo Judith; Twilley, Danielle; Lall, Namrita; Ray, Suprakas Sinha (American Chemical Society, 2021-10-21)

This study investigated a unique one-pot microwave- assisted green synthesis method of gold (Au) and silver (Ag) nanoparticles (NPs) using cannabidiol (CBD) as a capping and reducing agent. Furthermore, Au and Ag NPs ...
One-step synthesis of metal oxide nanoparticles using cannabidiol: characterisation and cytotoxicity assessment in human keratinocyte cells

Josiah, Andrea Jess; Pillai, Sreejarani K.; Cordier, Werner; Nell, Margo Judith; Lall, Namrita; Twilley, Danielle; Ray, Suprakas Sinha (Wiley, 2024-02)

Please read abstract in the article.
Self-isomerized−cyclometalated rhodium NHC complexes as active catalysts in the hydrosilylation of internal alkynes

Van Vuuren, Estefan; Malan, F.P. (Frederick); Cordier, Werner; Nell, Margo Judith; Landman, Marile (American Chemical Society, 2022-02)

Please read abstract in the article.

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Browsing Natural and Agricultural Sciences by UP Author "Nell, Margo Judith"

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