Browsing Natural and Agricultural Sciences by Supervisor "Neitz, A.W.H. (Albert Walter Herman)"
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Browsing Natural and Agricultural Sciences by Supervisor "Neitz, A.W.H. (Albert Walter Herman)"
Now showing items 1-15 of 15
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(University of Pretoria, 2015)Lipopolysaccharides (LPS), when released from the outer membrane of Gram-negative bacteria, bind to macrophages, inducing production of pro-inflammatory cytokines and mediator molecules. In addition, associated overproduction ...
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(University of Pretoria, 2014)With the emergence of drug resistant bacteria, the need for new antimicrobial agents is growing. Antimicrobial peptides (AMPs) are natural antibiotics which have a broad spectrum of activity and also due to a great diversity ...
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(University of Pretoria, 2011-06-27)Most studies on innate immunity in ticks have focused on the antimicrobial peptides from hemolymph, such as defensins and lysozyme, while less is known about bacterial recognition molecules, or antimicrobial mechanisms in ...
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(University of Pretoria, 2007-05-02)The high incidence of malaria, coupled to the increasing occurrence of parasite resistance against commonly used anti-malaria drugs and the absence of an effective vaccine, makes the implementation of alternative strategies ...
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(University of Pretoria, 2016)The rapid increase of multi-drug resistant bacteria and associated deaths has stimulated research into the development of novel therapeutic options. Antimicrobial peptides (AMPs) display a high therapeutic potential in ...
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(University of Pretoria, 2002)Please read the abstract in the section 00front of this document
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(University of Pretoria, 2005-10-07)Invertebrates do not possess an adaptive immune system, but rely on several mechanisms similar to the innate immune system of mammals. The synthesis and release of a host of potent antimicrobial proteins is an important ...
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The mechanisms regulating exocytosis of the salivary glands of the soft tick,Ornithodoros savignyi (University of Pretoria, 2007-02-15)Numerous bioactive compounds are secreted from large dense core granules in tick salivary glands during feeding. Investigations into the signalling pathways regulating secretion indicated that they are similar for Argasidae ...
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(University of Pretoria, 2009-04-16)Haemostasis is a highly regulated system, involving a myriad of cell types (endothelium, immune cells, platelets, etc.), proteins (enzymes, receptors, etc.) and signalling molecules (sterols, nucleotides, etc.). Haematophagous ...
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(University of Pretoria, 2010-03-12)Ticks are blood feeding ectoparasites that ingest large volumes of vertebrate blood. They are the most important arthropods that are capable of transmitting pathogens which cause disease in humans and domestic animals. ...
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(University of Pretoria, 2006-11-21)Commercial (high-grade) BaS04 selectively adsorbs two proteins from crude 0. savignyi salivary gland extracts. They co-purify during reversed-phase HPLC, but can be separated by hydrophobic-interaction chromatography. Both ...
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(University of Pretoria, 2013)Tick proteins functioning in vital physiological processes such as blood meal uptake, digestion and reproduction are potential targets for anti-tick vaccines, since vaccination could disrupt these essential functions and ...
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(University of Pretoria, 2013)The rapid geographic expansion of the cattle tick species, Rhipicephalus microplus, as well as the introduction of diseases into previously unaffected areas and the increased incidence of acaricide resistance in this species ...
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(University of Pretoria, 2013)In this study the structural characteristics and antibacterial activities of two peptides derived from the carboxy-terminal of a tick defensin were investigated. Two defensin isoforms (OsDef1 and OsDef2) were previously ...
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(University of Pretoria, 2013)Overuse of conventional antibiotics has led to increased multidrug resistant micro-organisms. Therefore, development of alternative drugs with new mechanisms of action in the control of resistant micro-organisms is urgently ...
Now showing items 1-15 of 15