Serological evidence of Rift Valley fever virus circulation in sheep and goats in Zambezia Province, Mozambique

Show simple item record

dc.contributor.author Fafetine, Jose Manuel
dc.contributor.author Neves, L.C.B.G.D. (Luís)
dc.contributor.author Thompson, P.N. (Peter N.)
dc.contributor.author Paweska, Janusz Tadeusz
dc.contributor.author Rutten, Victor P.M.G.
dc.contributor.author Coetzer, Jacobus A.W.
dc.date.accessioned 2014-02-11T10:48:27Z
dc.date.available 2014-02-11T10:48:27Z
dc.date.issued 2013-02-28
dc.description.abstract Rift Valley fever (RVF) is endemic in most parts of Africa and has also been reported to occur in the Arabian Peninsula. It is responsible for significant morbidity and mortality, particularly in livestock, but also in humans. During the last two decades several outbreaks of RVF have been reported in countries in Southern Africa. In contrast to other countries, no clinical disease has been reported in Mozambique during this period. In a serological study conducted in 2007 in five districts of Zambe´zia Province, Mozambique, of a total of 654 small ruminants sampled (277 sheep and 377 goats), 35.8% of sheep sera and 21.2% of goat sera were positive for RVF virus (RVFV) antibodies in a virus neutralization test (VN) and in an IgG enzymelinked immunosorbent assay (ELISA). In 2010, a cross-sectional survey was conducted in 313 sheep and 449 goats in two districts of the same province. This study revealed an overall seropositivity rate of 9.2% in sheep and 11.6% in goat and an increased likelihood of being seropositive in older animals (OR = 7.3; p,0.001) using an IgG ELISA. 29 out of 240 animals assessed for RVF specific IgM by ELISA were positive, suggesting recent exposure to RVFV. However, a longitudinal study carried out between September 2010 and April 2011 in a cohort of 125 of these animals (74 sheep and 51 goats) failed to demonstrate seroconversion. The results of the study indicate that RVFV circulates sub-clinically in domestic small ruminants in Zambe´ zia Province. en
dc.description.librarian am2014 en
dc.description.librarian ab2014
dc.description.sponsorship The work was supported by the SIDA/SAREC project UEM, the Italian Project at the Biotechnology Center – UEM (AID 9397), and by the Utrecht University, The Netherlands. en
dc.description.uri http://www.plosntds.org en
dc.identifier.citation Fafetine J, Neves L, Thompson PN, Paweska JT, Rutten VPMG, et al. (2013) Serological Evidence of Rift Valley Fever Virus Circulation in Sheep and Goats in Zambe´ zia Province, Mozambique. PLoS Negl Trop Dis 7(2): e2065. DOI: 10.1371/journal.pntd.0002065 en
dc.identifier.issn 1935-2727
dc.identifier.other 10.1371/journal.pntd.0002065
dc.identifier.other 7403220452
dc.identifier.other J-2534-2013
dc.identifier.uri http://hdl.handle.net/2263/33396
dc.language.iso en en
dc.publisher Public Library of Science en
dc.relation.requires Adobe Acrobat Reader en
dc.rights © 2013 Fafetine et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License en
dc.subject Virus circulation en
dc.subject Sheep en
dc.subject Goats en
dc.subject Zambezia Province, Mozambique en
dc.subject RVF en
dc.subject.lcsh Rift Valley fever en
dc.subject.lcsh Zoonoses en
dc.subject.lcsh Sheep -- Diseases en
dc.subject.lcsh Goats -- Diseases en
dc.subject.lcsh Veterinary serology en
dc.title Serological evidence of Rift Valley fever virus circulation in sheep and goats in Zambezia Province, Mozambique en
dc.type Article en


Files in this item

This item appears in the following Collection(s)

Show simple item record