Molecular epidemiology of rabies virus in South Africa

Show simple item record Von Teichman, B.F. Rabies in Southern and Eastern Africa. Workshop. (1993, Pretoria, South Africa)
dc.contributor.editor Verwoerd, Daniel Wynand
dc.contributor.upauthor Nel, Louis Hendrik
dc.contributor.upauthor Thomson, G.R. (Gavin) 2014-01-28T07:03:57Z 2014-01-28T07:03:57Z 2013 1993
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en
dc.description.abstract Nucleic acid sequence analysis was used to determine the phylogenetic relationships amongst rabies viruses isolated from typical canid hosts such as bat-eared fox, jackal and dog in South Africa (SA). Geographical factors were taken into account in the selection of isolates and three different regions within the genomes of the isolates were compared for their use as phylogenetic indicators. The three genome regions, being the cytoplasmic domain of the G-gene, the G-L intergenic pseudogene and the antigenic domain II of the N-gene were found to differ in terms of the degree of nucleic acid conservation, but produced similar results when analyzed phylogenetically. The SA canid isolates were found to be closely related and could clearly be distinguished from all other rabies virus groups for which sequence data is available. In addition four SA mongoose rabies isolates were studied which were shown to be distant from the SA canid rabies virus group as well as from any other rabies viruses (or group) for which sequence data is available. Our results also indicate that spillover between the distinct canid and viverrid host reservoirs may occur. en
dc.description.librarian mn2014
dc.description.sponsorship Agricultural Research Council. en
dc.identifier.citation Nel, LH, Thomson, GR & Von Teichman, BF 1993, 'Molecular epidemiology of rabies virus in South Africa’, Onderstepoort Journal of Veterinary Research, vol. 60, no. 4, pp. 301-306. en
dc.identifier.issn 0330-2465
dc.language.iso en en
dc.publisher Published by the Agricultural Research Council, Onderstepoort Veterinary Institute en
dc.rights © ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital). en
dc.subject Veterinary medicine en
dc.subject Rabies in southern and eastern Africa. Proceedings of a workshop held at the Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa, 3-5 May 1993 en
dc.subject The molecular epidemiology of African Lyssaviruses en
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title Molecular epidemiology of rabies virus in South Africa en
dc.type Other en

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