Re-defining the extent of malaria transmission in South Africa : implications for chemoprophylaxis

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dc.contributor.author Morris, Neil Kenneth
dc.contributor.author Frean, J.
dc.contributor.author Baker, Lee
dc.contributor.author Ukpe, I.S. (Indongesit Sunday)
dc.contributor.author Barnes, K.I.
dc.contributor.author Kruger, P.
dc.contributor.author Mabuza, A.
dc.contributor.author Raswiswi, E.
dc.contributor.author Maharaj, Rajendra
dc.contributor.author Blumberg, Lucille H.
dc.contributor.author Moonasar, Devanand
dc.date.accessioned 2013-11-21T09:28:37Z
dc.date.available 2013-11-21T09:28:37Z
dc.date.issued 2013-11
dc.description.abstract BACKGROUND. Malaria case numbers reported in South Africa have reduced considerably over the last decade, necessitating a revision of the national risk map to guide malaria prevention, including the use of chemoprophylaxis. OBJECTIVES. To update the national malaria risk map based on recent case data and to consider the implications of the new transmission profile for guiding prophylaxis. METHODS. The geographical distribution of confirmed malaria cases detected both passively and actively over the last six malaria seasons was used to redefine the geographical distribution and intensity of malaria transmission in the country. RESULTS. The national risk map was revised to reflect zones of transmission reduced both in their extent and their intensity. Most notably, the area of risk has been reduced in the north-western parts of Limpopo Province and is limited to the extreme northern reaches of KwaZulu- Natal Province. Areas previously considered to be of high risk are now regarded to be of moderate risk. CONCLUSION. Chemoprophylaxis is now only recommended from September to May in the north-eastern areas of Limpopo and Mpumalanga Provinces. The recommended options for chemoprophylaxis have not changed from mefloquine, doxycycline or atovaquone-proguanil. en_US
dc.description.librarian am2013 en_US
dc.description.librarian ay2013 en
dc.description.uri http://www.samj.org.za en_US
dc.identifier.citation Morris, N, Frean, J, Baker, L, Ukpe, IS, Barnes, KI, Kruger, P, Mabuza, A, Raswiswi, E, Maharaj, R, Blumberg, L & Moonasar, D 2013, 'Re-defining the extent of malaria transmission in South Africa : implications for chemoprophylaxis', South African Medical Journal, vol. 103, no. 11, pp. 861-864. en_US
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.identifier.other 10.7196/SAMJ.7533
dc.identifier.uri http://hdl.handle.net/2263/32558
dc.language.iso en en_US
dc.publisher Health and Medical Publishing Group en_US
dc.rights Health and Medical Publishing Group en_US
dc.subject Malaria, South Africa en_US
dc.subject Chemoprophylaxis en_US
dc.subject Limpopo Province, South Africa en_US
dc.subject.lcsh Malaria -- South Africa en
dc.title Re-defining the extent of malaria transmission in South Africa : implications for chemoprophylaxis en_US
dc.type Article en_US


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