dc.contributor.author |
Botha, C.J. (Christoffel Jacobus)
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dc.contributor.author |
Naude, T.W.
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dc.contributor.author |
Swan, Gerry E.
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dc.contributor.editor |
Verwoerd, Daniel Wynand |
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dc.contributor.upauthor |
Guthrie, Alan John
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dc.date.accessioned |
2013-11-20T06:08:15Z |
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dc.date.available |
2013-11-20T06:08:15Z |
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dc.date.created |
2013 |
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dc.date.issued |
1992 |
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dc.description |
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. |
en |
dc.description.abstract |
An in vitro technique for haemolysing ovine red blood cells with copper sulphate was standardized to induce c 50% haemolysis with 0,5 mM CuSO₄ after incubation for 14 h at 38°C. This technique was then applied to test the efficacy of trientine and d-penicillamine in preventing haemolysis. Trientine concentrations of 0,5; 1,0 and 1,5 mM were found to be the most effective (P<0,05) in reducing copper-induced haemolysis. One and 1,5 mM concentrations of d-penicillamine were also effective (P< 0,05), but in this experiment a 0,5 mM concentration failed to protect the erythrocytes. |
en |
dc.description.librarian |
mn2013 |
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dc.description.sponsorship |
Palabora Mining Company. |
en |
dc.identifier.citation |
Botha, CJ, Naude, TW, Swan, GE & Guthrie, AJ 1992, 'Evaluation of the efficacy of d-penicillamine and trientine as copper chelators using an in vitro technique involving ovine red blood cells’, Onderstepoort Journal of Veterinary Research, vol. 59, no. 3, pp. 191-195 |
en |
dc.identifier.issn |
0330-2465 |
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dc.identifier.other |
7102127047 |
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dc.identifier.other |
7006558662 |
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dc.identifier.other |
I-7222-2013 |
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dc.identifier.other |
7006535470 |
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dc.identifier.other |
J-6375-2013 |
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dc.identifier.other |
0000-0001-7729-9918 |
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dc.identifier.other |
O-5991-2014 |
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dc.identifier.uri |
http://hdl.handle.net/2263/32520 |
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dc.language.iso |
en |
en |
dc.publisher |
Published by the Agricultural Research Council, Onderstepoort Veterinary Institute. |
en |
dc.rights |
©South Africa. Dept. of Agricultural Technical Services. ©University of Pretoria. Dept. of Library Services (digital). |
en |
dc.subject |
Veterinary medicine |
en |
dc.subject |
Sheep |
en |
dc.subject.lcsh |
Veterinary medicine -- South Africa |
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dc.title |
Evaluation of the efficacy of d-penicillamine and trientine as copper chelators using an in vitro technique involving ovine red blood cells |
en |
dc.type |
Article |
en |