• Synthesis, complexion and reactivity studies of novel bis (1,2,3-triazol-5-ylidene) carbazolide ligands 

  Kleinhans, George (University of Pretoria, 2014-10)

  Please read abstract in article.
• The origin of electron density accumulation within CH,HC contacts in biphenyl : a theoretical study 

  Bates, Thomas Günter (University of Pretoria, 2021)

  The primary focus of this work is the investigation into the nature and origin of the electron density between the ortho-hydrogens in the higher energy, planar transition state of biphenyl. This interaction has been the ...
• Production of calcium carbonate from phosphogypsum wastes 

  Ondo Ndjimbi, Lilian Urlain (University of Pretoria, 2014)

  Phosphogypsum is a waste generated during the production of wet phosphoric acid from phosphate rocks. Numerous studies have attempted to find applications for phosphogypsum, but its composition is generally limiting its ...
• Supercapacitive Properties of Nanocarbons Modified with Manganese Oxide Nanoparticles and Metallotetrapyrazinoporphyrazines 

  Lekitima, Joel Ntotole (University of Pretoria, 2013)

  This dissertation describes the electrochemical properties of nanocarbons (multiwalled carbon nanotubes (MWCNTs) and graphene oxide (GO)) incorporated with manganese dioxide (MnO2) and metallotetrapyrazinoporphyrazines ...
• Synthesis and fluorescent labelling of model mycolic acids 

  Kayembe, Jean Pierre (University of Pretoria, 2014)

  Mycolic Acids (MAs) are long chain α-alkyl-β-hydroxy fatty acids that form part of the cell wall of Mycobacterium species and a few other genera. They play an important role in steering the host-pathogen relationship to ...
• Microwave-assisted synthesis of palladium-based core-shell nanocatalysts and iron phthalocyanines and their applications in direct alkaline alcohol fuel cells 

  Fashedemi, Omobosede Oluwatoyin (University of Pretoria, 2013)

  Palladium-based nano-alloys are well-known for their unique electrocatalytic properties for direct alcohol alkaline fuel cells (DAAFCs). This dissertation describes, for the first time, the synthesis of a novel ternary ...
• Structural And Magnetic Investigation Of Hybrid Compound Of Saturated Primary, secondary And tertiary Organic Amines And Metal Halides 

  Bothma, Shalene Natalia (University of Pretoria, 2014)

  Organic‐inorganic hybrid materials combine an inorganic component with an organic component at the nanoscale, while potentially retaining the properties of both components. In the current study the structural characteristics ...
• The synthesis of analogues and bioisosteres of the acetylcholinesterase inhibitor donepezil in an attempt to identify novel anti-Alzheimer’s agents 

  Reinhardt, Anshe Michelle (University of Pretoria, 2020)

  As part of an in-house project, the CSIR-housed BioFocus library composed of approximately 20’000 thousand compounds were screened for activity against AChE by van der Westhuizen (PhD candidate) using a combination of in ...
• A theoretical study on the nature of organometallic carbene bonding in Titanium Schrock carbene complexes 

  De Beer, Shane (University of Pretoria, 2020)

  Although various organometallic carbene complexes have found use in industry or research, they still lack some fundamental footing in theory. These complexes have found significant use in catalysis. This is especially true ...
• Identication of semiochemicals from four major insect pests of Eucalyptus and Pinus species in South Africa 

  Bouwer, Marc Clement (University of Pretoria, 2014)

  The chemical ecology for key insect pests in South Africa's commercial Pinus and Eucalyptus plantations are explored in this thesis. The main aim was to discover and characterize semiochemical compounds that explain ...
• Chemical profiling of the human skin surface for malaria vector control using combined chromatography and mass spectrometry techniques 

  Wooding, Madelien (University of Pretoria, 2021)

  The World Health Organisation (WHO) estimated that 216 million cases of malaria occurred worldwide in 2016 with most of the cases diagnosed in the African Region (90%) (WHO, World Malaria Report, 2017). Odour mosquito lures ...
• Development of Siphonochilus aethiopicus as a treatment for colds and influenza and gas chromatographic analysis of volatiles of an insect repellent 

  Kruger, Leylene (University of Pretoria, 2020)

  Part A of the study focuses on Siphonochilus aethiopicus, also known as African ginger, to determine its antiviral properties and the compounds responsible for the biological activity. African ginger is one of the most ...
• Comparison of pesticide deposition sampling methods for spray drift of atrazine 

  Munjanja, Basil Kudakwashe (University of Pretoria, 2019)

  Off-target deposition is a potential route of pesticide entry into the environment. To determine off-target deposition of pesticides, various deposition samplers are used. A study was carried out to compare a number of ...
• Isolation of antiplasmodial naphthylisoquinoline alkaloids from Ancistrocladus sp. through bioassay-guided fractionation 

  Mianda, Mutombo Sephora (University of Pretoria, 2019)

  Ancistrocladus is the only genus in the Ancistrocladaceae family and together with the closely related Dioncophyllaceae, they produce naphthylisoquinoline (NIQ) alkaloids. This class of compounds exhibits a very interesting ...
• A theoretical study of the mechanism of (S) proline-catalysed aldol reactions 

  Dhimba, George (University of Pretoria, 2020)

  In this study, the novel, reaction energy profile-fragment attributed molecular system energy change (REP-FAMSEC) was applied in studying mechanisms of chemical reactions. The applicability of the REP-FAMSEC protocol was ...
• Synthesis and properties of Fischer (multi)carbene complexes of condensed thiophenes 

  Lamprecht, Zandria (University of Pretoria, 2020-09)

  The oxidative cleaving of a rhenium–rhenium bond by bromine in binuclear Fischer carbene complexes proves to be an effective method to prepare mononuclear bromido-carbene complexes. The reaction of mono- and dilithiated ...
• An experimental and computational investigation of the magnetic properties of organic-inorganic hybrids 

  Coetzee, Stefan (University of Pretoria, 2020)

  Magnetochemistry is a multidisciplinary research field that is at the frontier of the development of Quantum Age materials. The purposeful design of materials originates from a fundamental understanding of the factors that ...
• Synthesis and application of Fischer carbene complexes of group 6, 8 and 9 transition metals 

  Moeng, Mmushi Moses (University of Pretoria, 2020)

  A range of novel Fischer carbene complexes (FCCs) of group 6 (Cr and W), 8 (Fe) and 9 (Co) metals was prepared using the classical Fischer route, and their electronic and steric properties evaluated. For W(0) and Cr(0), ...
• Utilization of flow chemistry for the synthesis of bupropion, fluoxetine and amitraz 

  Van Wyk, Lorinda T. (University of Pretoria, 2020)

  In recent years, the utilization of flow technology in academic research groups has become increasingly popular especially with regards to the preparation of fine organic compounds such as natural products and Active ...
• Combining in silico and in vitro approaches to discover novel inhibitors of Acetylcholinesterase 

  Van der Westhuizen, Carl Johan (University of Pretoria, 2020)

  Alzheimer’s disease (AD) is the most common neurodegenerative disease which is a significant socio-economic problem. The number of patients affected by the disease is increasing at an alarming rate, largely due to expanding ...

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