Browsing Theses and Dissertations (Bioinformatics and Computational Biology Unit) by Type "Dissertation"

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In silico inference of immunological relationship between protein antigens based on their cytotoxic T-lymphocyte epitope repertoires

Smidt, Werner (University of Pretoria, 2011-06-07)

The importance of Cytotoxic T-Cell (CTL) reponses during the course of intracellular infections has received a lot of attention during the past few decades. CTLs respond to epitopes presented by the Major Histocompatibility ...
Investigation of cystic fibrosis transmembrane conductance regulator variants in South African patients with cystic fibrosis

Le Grange, Odette (University of Pretoria, 2023)

Cystic Fibrosis is a genetic disease caused by variants in the CFTR gene. It is one of the most thoroughly studied genetic diseases, with remarkable advances being seen in the ability to diagnose and specifically treat CF ...

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