Trends and ethnic disparities in oral and oro-pharyngeal cancers in South Africa, 1992-2001

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dc.contributor.author Ayo-Yusuf, Olalekan A.
dc.contributor.author Lalloo, R.
dc.contributor.author Johnson, N.W.
dc.date.accessioned 2013-11-12T13:45:32Z
dc.date.available 2013-11-12T13:45:32Z
dc.date.issued 2013-05
dc.description The authors thank Patricia Kellet for her valuable support in extracting the data and the National Cancer Registry for making the data available. en_US
dc.description.abstract OBJECTIVE: To describe trends in the epidemiology of oral and of oro-pharyngeal (OAP) cancers in South Africa for the latest period available. METHODS: Data were obtained from the South African pathology- based National Cancer Registry. All new cases of OAP cancers diagnosed and confirmed histologically from 1992 to 2001 are included for the ICD-10 sites C00 to C14, excluding those involving the major salivary glands (C07- C08) and the nasopharynx (C11). OAP cancer incidence is reported by demographics (gender, age, race/ethnicity) and the anatomical sites involved. The analysis on anatomical sites was restricted to squamous cell carcinomas. RESULTS: Overall, males had a much higher OAP cancer incidence rate (world age-Standardised incidence rate [ASIR]= 7.01/100 000 per year) than females (ASIR=1.99). However, among Asian/Indian South Africans, OAP cancer incidence was higher among females (ASIR=4.60) than among males (ASIR=3.80). OAP cancer, excluding those involving the lip, was highest among Coloureds (ASIR=5.72) and lowest among Blacks (ASIR=3.16). OAP cancer incidence was stable overall, but incidence rates increased significantly among Coloured South Africans over the period under review (p≤0.05). Cancer specifically involving the oro-pharyngeal was most common among Coloureds and showed an increasing trend during the period under review. CONCLUSIONS: Variations in the incidence of OAP cancers by gender, race/ethnicity and anatomic site indicate a need for culturally-targeted reductions in major risk factors, including promoting tobacco cessation and prevention of risky alcohol use. The implications of the role of the human papillomavirus (HPV) in the prevention of squamous cell carcinomas involving the oro-pharyngeal in South Africa require further investigation. en_US
dc.description.librarian am2013 en_US
dc.description.librarian ay2013 en
dc.description.uri http://www.sada.co.za en_US
dc.identifier.citation Ayo-Yusuf, OA, Lalloo, R & Johnson, NW 2013, 'Trends and ethnic disparities in oral and oro-pharyngeal cancers in South Africa, 1992-2001', South African Dental Journal, vol. 68, no. 4, pp. 168-173. en_US
dc.identifier.issn 1029-4864
dc.identifier.uri http://hdl.handle.net/2263/32412
dc.language.iso en en_US
dc.publisher South African Dental Association en_US
dc.rights South African Dental Association. This article is embargoed by the publisher until 2014. en_US
dc.subject Oral and oro-pharyngeal cancer en_US
dc.subject Epidemiology en_US
dc.subject Tobacco en_US
dc.subject Alcohol en_US
dc.subject Inequalities en_US
dc.subject Ethnic disparities en_US
dc.subject Trends en_US
dc.subject HPV en_US
dc.subject.lcsh Mouth -- Cancer -- Diagnosis -- South Africa en
dc.title Trends and ethnic disparities in oral and oro-pharyngeal cancers in South Africa, 1992-2001 en_US
dc.type Article en_US


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