Abstract:
Aim To test the effectiveness of motivational interviewing (MI) to reduce the risk of an alcohol exposed pregnancy
(AEP) in a high-risk population. Design Randomized controlled trial. Setting Rural population in the Western
Cape, South Africa. Participants A total of 165 women aged 18–44 years at risk of AEP. Intervention Five-session
MI intervention. Measurements Structured questionnaires were administered pre-intervention and at 3 and 12
months follow-up. The primary outcome measure was AEP at 12 months. Secondary outcomes were AEP at 3 months,
and alcohol use and effective contraception at 3 and 12 months. Findings There was a significant difference in the
decline in the proportion of women at risk for an AEP in the MI group at 3 months (50 versus 24.59%; P = 0.004),
maintained at 12 months (50.82 versus 28.12%; P = 0.009). In an intention-to-treat analysis these differences were
also significant (32.93 versus 18.07%; P = 0.029; and 37.80 versus 21.69%; P = 0.024, respectively). The odds ratio
for no longer being at risk of an AEP (MI versus control) at 12 months was 2.64 [95% confidence interval (CI):
1.18–5.94]. In the intention-to-treat analysis this ratio was 2.19 (95% CI: 1.05–4.65). Conclusions A five-session
motivational interviewing intervention was found to be effective with women at risk of an alcohol-exposed pregnancy,
and could be implemented as part of routine primary care clinic services in similar populations. The message of ‘no
alcohol in pregnancy’ should be adapted to include better family planning and early recognition of pregnancy.
