Browsing Theses and Dissertations (University of Pretoria) by Supervisor "Visagie, M.H. (Michelle Helen)"
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Browsing Theses and Dissertations (University of Pretoria) by Supervisor "Visagie, M.H. (Michelle Helen)"
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(University of Pretoria, 2019)Tumourigenic cells utilize aberrant metabolic process that supports the biosynthetic requirements for hyperproliferation, survival and prolonged maintenance characterised by glucose metabolism to lactate dehydrogenase ...
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(University of Pretoria, 2021)Cancer is a leading cause of mortality with close to 10 million deaths reported in 2020 with lung- and breast cancer being the most diagnosed types of cancer. Papaverine (PPV), a natural occurring, non-narcotic benzylisoquinoline ...
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(University of Pretoria, 2020)2-Methoxyestradiol (2ME), a 17β-estradiol metabolite, exerts anticancer properties however, the compound was found to possess low bioavailability. This resulted in the in silico-design of 2ME analogues with a sulphamoyl ...
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