Browsing Theses and Dissertations (University of Pretoria) by Supervisor "Van den Bout, Jan Iman"
- UPSpace Home
- →
- University of Pretoria: Research Output
- →
- Theses and Dissertations (University of Pretoria)
- →
- Browsing Theses and Dissertations (University of Pretoria) by Supervisor
JavaScript is disabled for your browser. Some features of this site may not work without it.
Browsing Theses and Dissertations (University of Pretoria) by Supervisor "Van den Bout, Jan Iman"
Now showing items 1-6 of 6
-
(University of Pretoria, 2023-03-03)The recent advancements in gene editing have provided scientists with a powerful tool for the investigation of the role of individual proteins in cellular physiology and disease. Gene editing was preceded by another powerful ...
-
(University of Pretoria, 2018)Triple-negative breast cancer (TNBC) lacks the expression of estrogen receptor-alpha, progesterone receptor and human epidermal growth factor receptor 2 (HER2). The lack of dependence on estrogen by TNBC cells makes ...
-
Development of a breast cancer spheroid model for use in drug discovery and cancer biology research (University of Pretoria, 2020)The screening of lead compounds during cancer drug discovery still results in many hits that never reach the clinic. This is in part due to the distance between 2D cell culture, which is mostly used for screening assays ...
-
(University of Pretoria, 2022)The ability of cells to communicate constitutes an important characteristic of all multi- cellular organisms. Cells participate in a continuous relay of information between their environment and other cells. These connections ...
-
(University of Pretoria, 2021-02-10)Kisspeptin receptor, also known as KISS1R, is the endogenous receptor for the ligand peptide, kisspeptin. It is a G-protein coupled receptor that couples through the Gαq/11 pathway. It has been shown that KISS1R activation ...
-
(University of Pretoria, 2019)Breast cancer is a commonly diagnosed cancer in women, with increasing diagnosis and mortality rates. The triple-negative sub-type of the disease is characterised by lack of hormone-receptor overexpression, exhibition of ...
Now showing items 1-6 of 6