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Browsing Theses and Dissertations (University of Pretoria) by Subject "Genetic stability"

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Laboratory Detection and Gene Cassette Stability of the Novel Extended-Spectrum Beta-Lactamase, GES-2 from Pseudomonas aeruginosa

Weldhagen, Gerhard Frederick (University of Pretoria, 2004)

Extended-spectrum beta-lactamases (ESBLs) in Pseudomonas aeruginosa tend to be geographically scattered, such as GES-2, which partially compromises the efficacy of imipenem. The G170N mutation, ascribed to a CC to AA base ...

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