For companion animal medicine, Feline Infectious Peritonitis (FIP) is an important disease - it is fatal, and prevention is a challenge. FIP is a sporadic viral condition - a contradiction in terms. The explanation: mutants of a coronavirus (CoV) that is endemic in most feline populations, arise in individual cats, change their tropism
from enterocyte to macrophage and cause a polyserositis with pyogranulomas. The FIP causing variants are usually not transmitted, and there is no epidemic spread.
PowerPoint presentation and curriculum vitae of Prof Marian C. Horzinek. This Arnold Theiler Memorial Lecture was delivered on September 5, 2013 at the University of Pretoria, Faculty of Veterinary Medicine, Onderstepoort. Marian C. Horzinek is Professor Emeritus of Virology and Viral Diseases of the Faculty of Veterinary Medicine, Utrecht University and former Director of the Graduate School of Animal Health, Utrecht University.