Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection

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Authors

Osuagwuh, Uchebuchi I.
Bagla, Victor Patrick
Venter, Estelle Hildegard
Annandale, C.H. (Cornelius Henry)
Irons, Pete Charles

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

Twelve serologically negative bulls were used, six were vaccinated with a modified live LSD vaccine and six unvaccinated. All were then experimentally infected with a virulent field strain of LSDV. No clinical abnormality was detected following vaccination, and mild clinical signs were seen in four vaccinated bulls following challenge. Virus was not found in semen of vaccinated bulls. Two of the unvaccinated bulls developed severe LSD and four showed mild symptoms, all excreted the virus in the semen following challenge. This study confirmed the ability of LSD vaccination to prevent the excretion of LSDV in semen of vaccinated bulls.

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Keywords

Neethling strain vaccine

Sustainable Development Goals

Citation

Osuagwuh, UI, Bagla, V, Venter, EH, Annandale, CH & Irons, PC 2007, ‘Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection’, Vaccine, vol. 25, no. 12, pp. 2238-2243.[http://www.sciencedirect.com/science/journal/0264410X]