Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection
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Date
Authors
Osuagwuh, Uchebuchi I.
Bagla, Victor Patrick
Venter, Estelle Hildegard
Annandale, C.H. (Cornelius Henry)
Irons, Pete Charles
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Twelve serologically negative bulls were used, six were vaccinated with a modified live LSD vaccine and six unvaccinated. All were then experimentally infected with a virulent field strain of LSDV. No clinical abnormality was detected following vaccination, and mild clinical signs were seen in four vaccinated bulls following challenge. Virus was not found in semen of vaccinated bulls. Two of the unvaccinated bulls developed severe LSD and four showed mild symptoms, all excreted the virus in the semen following challenge. This study confirmed the ability of LSD vaccination to prevent the excretion of LSDV in semen of vaccinated bulls.
Description
Keywords
Neethling strain vaccine
Sustainable Development Goals
Citation
Osuagwuh, UI, Bagla, V, Venter, EH, Annandale, CH & Irons, PC 2007, ‘Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection’, Vaccine, vol. 25, no. 12, pp. 2238-2243.[http://www.sciencedirect.com/science/journal/0264410X]