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Browsing Pharmacology by Type "Postprint Article"
Now showing items 1-20 of 56
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(Elsevier, 2019-11)Parkinson’s disease, characterised by loss of dopaminergic neurons in the substantia nigra of the brain, is attributed to oxidative stress and mitochondrial dysfunction. As no cure is available, and dopamine-replacement ...
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(Elsevier, 2012-06)A series of new neutral mononuclear or dinuclear gold(I) complexes and a cyclic cationic tetranuclear amidogold(I) complex comprising of the phosphines 1,2- bis(dimethylphosphino)ethane (dmpe), μ-1,2–bis(diphenylphosphino)ethane ...
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(Wiley, 2015-06)Humic substances are effective in the suppression of delayed type hypersensitivity, rat paw oedema, a graftversus- host reaction and contact hypersensitivity in rats. They reduce the C-reactive protein levels of ...
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(Elsevier, 2009-07)The anti-tumour activity of the Au (I) phosphine complex [Au(dppe2]Cl was first discovered in the mid 1980s although promising results were obtained it did not pass clinical studies because of its toxicity to organs such ...
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(Springer, 2015-06)Contemporary chemotherapy is limited by disseminated, resistant cancer. Targeting nanoparticulate drug delivery systems that encapsulate synergistic drug combinations are a rational means to increase the therapeutic ...
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(Elsevier, 2011)Alzheimer's disease (AD) is the most common type of dementia in the aging population. Enhancement of acetylcholine levels in the brain is one means of treating the disease. However, the drugs presently used in the management ...
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(Wiley, 2016-12)Cases of poisoning by p-phenylenediamine (PPD) are detected sporadically. Recently an article on the development and validation of a LC-MS/MS method for the detection of PPD and its metabolites, N-acetyl-p-phenylenediamine ...
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(Wiley, 2018-01)OBJECTIVES : Whole plants of Boerhavia diffusa L. are widely used medicine in Ghana and other tropical countries, for the treatment of wounds and other ailments. The aim of the study was to determine the ability of sequential ...
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(Springer, 2022-10)As global health concerns become more complex, technological intervention is needed to achieve the Sustainable Development Goal. This study explores the use of the internet of things (IoT) and augmented reality (AR) ...
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(Royal Society of Chemistry, 2018-03)The aim of this study was to evaluate the protective effect of folate against methomyl-induced toxicity on the kidneys and testes of male rats. Adult male albino rats were divided into four groups; Group I served as the ...
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(Elsevier, 2018-03)Resveratrol is a naturally occurring polyphenol that has been shown to elicit a variety of beneficial effects in vitro. Translating these gains to in vivo and clinical settings has proven to be a major challenge, because ...
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(Springer, 2007-10)OBJECTIVES:The effects of two humate products were compared to that of prednisolone on a contact hypersensitivity rat model. METHODS: Rats, sensitized with dinitrofluorobenzene (DNFB), were placed on a daily oral treatment ...
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(Elsevier, 2018-01)INTRODUCTION : Traditional remedies remain a prominent form of therapy in developing countries, such as South Africa. Boophone disticha, or the poison bulb, is used for the treatments of wounds. There is generally a lack ...
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(Wiley-Blackwell, 2012-01)The objectives of this study were to evaluate the safety and anti-inflammatory and wound healing characteristics of carbohydrate derived fulvic acid (CHD-FA) in rats. A daily oral dosage of CHD-FA at 100mg/kg and higher ...
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(Elsevier, 2018-08)Hepatotoxicity remains a major challenge in drug development despite preclinical toxicity screening using hepatocytes of human origin. To overcome some limitations of reproducing the hepatic phenotype, more structurally ...
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(Wiley-Blackwell, 2010-09)The anti-inflammatory properties of products that contain high levels of humic acid, such as peat, sapropeles, and mumie, are well described. The aim of this study was to establish the clinical efficacy of brown coal-derived ...
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(Springer, 2015-12)Aloe vera gel is widely used in the treatment of an array of disturbances, especially skin disorders. The wound-healing effects have been attributed to its moisturizing and anti-inflammatory effects as well as its beneficial ...
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(Elsevier, 2019-08)As knowledge regarding mechanisms of pentachlorophenol (PCP) toxicity in neuronal cell lines is limited, the aim of the study was to evaluate the effects of PCP and its active metabolites, tetrachloro-1,4-benzoquinone ...
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(Elsevier, 2012-09-28)ETHNOPHARMACOLOGICAL RELEVANCE: Boophane disticha of the family Amaryllidaceae is used traditionally in southern Africa in the treatement of several neurological disorders. AIM OF THE STUDY: Although acetylcholinesterase ...
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(Royal Society of Chemistry, 2018-04)Five imino salicylidene based bifunctional chelators were developed in order to act as a multipurpose ligand system. The chelators, namely 5-methyl-2-(1,2,4-triazol-3-yliminomethyl)phenol, 2-(9-ethylcarbazol-3-yliminomet ...
Now showing items 1-20 of 56