Browsing Pharmacology by UP Author "Outhoff, Kim"

Browsing Pharmacology by UP Author "Outhoff, Kim"

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  • Outhoff, Kim (Medpharm, 2014)
    Acute non-specific low back pain, usually a result of muscle strains and ligament sprains from lifting, exercising or moving unexpectedly, is commonly encountered in primary care. At any given time, approximately one in ...
  • Outhoff, Kim (South African Academy of Family Practice/Primary Care, 2012)
    Agomelatine is a novel melatonergic antidepressant that restores disrupted biological rhythms, essentially by resetting the circadian clock. Two different, non-monoaminergic, and possibly synergistic pathways, appear to ...
  • Outhoff, Kim (OpenJournals, 2009-07)
    Depression and sexual dysfunction are both common in the general population. When they co-exist they have the potential to impact negatively on each other in a bidirectional manner. Medication used to treat depression may ...
  • Outhoff, Kim (OpenJournals Publishing, 2011-03)
    The human epidermal growth factor receptor 2 (HER2) is overexpressed in HER2-positive breast cancer. This confers characteristics associated with an overall poor prognosis, with early metastases to major visceral sites and ...
  • Outhoff, Kim (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2017)
    Bipolar disorder, characterised by alternating discrete episodes of (hypo)mania and depression, provides unique diagnostic and treatment challenges. Updated diagnostic (DSM-5) and current pharmacological treatment ...
  • Ker, James A.; Outhoff, Kim (Medpharm Publications, 2019-12)
    In general, heart failure is the end-stage manifestation of cardiovascular disease and is an important and increasing cause of morbidity worldwide. Acute heart failure, whether of new onset or an exacerbation of chronic ...
  • Ker, James A.; Outhoff, Kim (OASIS, 2019-03)
    Globally more than 1 billion people have hypertension and it is predicted that because of ageing populations and increasing sedentary lifestyles, this figure will rise to about 1.5 billion by 2025. Elevated blood pressure ...
  • Ker, James A.; Outhoff, Kim (AOSIS Open Journals, 2019-07)
    Chronic heart failure is common, debilitating, and often the culmination of pervasive cardiovascular insults that systematically undermine the heart’s circulatory capacity and invoke counterproductive neuro-hormonal ...
  • Outhoff, Kim (MedPharm Publications, 2016)
    Cognitive enhancement involves the non-medical use of illicit and/or prescription drugs, such as agents prescribed for attention deficit/hyperactive disorder (ADHD) and narcolepsy, usually in order to stay awake and to ...
  • Outhoff, Kim (Medpharm Publications, NISC (Pty) and Cogent, Taylor and Francis Group, 2019)
    At some point in their career, at least a third of doctors suffer personal health problems such as injury, aging, or physical and mental illness, which detract from their ability to function properly and to practice ...
  • Outhoff, Kim (Medpharm Publications, 2016)
    Since their introduction in 1987, statins have become the largest-selling prescription drugs worldwide, and have kept both the scientific and lay press captivated. This year alone has seen reports that statins may prevent ...
  • Outhoff, Kim (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016-05)
    Bipolar Disorder (BD) is characterised by alternating discrete episodes of depression and mania. Rational pharmacotherapy necessitates an appreciation of these different phases and of the possible underlying pathophysiology. ...
  • Outhoff, Kim (Medpharm, 2014)
    Acute otitis externa (AOE), or diffuse inflammation of the external ear canal, causes a range of symptoms, including otalgia, otorrhoea, hearing loss and itching. Despite AOE being common, with a 12-month prevalence of ...
  • Grommets 
    Outhoff, Kim (MedPharm Publications, 2015)
    Children younger than 7 years are at increased risk of otitis media because of their immature immune systems and poorly functioning eustachian tubes that normally ventilate the middle ear space and equalize pressure with ...
  • Hurrell, Tracey; Outhoff, Kim (Dove Medical Press, 2013-06-15)
    INTRODUCTION: Despite trastuzumab having enhanced selectivity for human epidermal growth factor receptor 2 (HER-2) overexpressing breast cancer cells, treatment is hampered by interindividual variation and tumors with high ...
  • Maepe, L.M.; Outhoff, Kim (Health and Medical Publishing Group, 2012-01)
    BACKGROUND: Reliable information about the prevalence of hypertension, which is a major contributor to cardiovascular disease in general and to coronary heart disease in particular, in different geographical regions is ...
  • Hurrell, Tracey; Outhoff, Kim (BioMed Central, 2013-10-11)
    BACKGROUND: Human epidermal growth factor receptor-2 (Her-2) is over expressed in approximately 25-30% of all primary breast tumors resulting in a distinctive breast cancer subtype associated with a poor prognosis and a ...
  • Outhoff, Kim; Greeff, O.B.W. (Oppel Bernhardt Wilhelm), 1948- (Oriental Scientific Publishing Company, 2018)
    The 15-25% of breast cancers that overexpress human epidermal growth factor receptor type 2 (Her-2) are aggressive and more difficult to treat with conventional chemotherapy than their oestrogen receptor positive (ER+) ...
  • Outhoff, Kim (MedPharm Publications, 2016)
    Intermittent or acute insomnia is common, and may sometimes require short-term treatment with an approved hypnotic agent. A diagnosis of insomnia disorder, however, indicates that night-time sleep is of poor quality and ...
  • Outhoff, Kim (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016)
    Intermittent or acute insomnia is common and may sometimes require short term treatment with approved hypnotic agents. A diagnosis of insomnia disorder, however, indicates that poor night-time sleep is chronic and is ...