Browsing Research Articles (Internal Medicine) by Title

Browsing Research Articles (Internal Medicine) by Title

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  • Rapid impact of effective treatment on transmission of multidrug-resistant tuberculosis 
    Dharmadhikari, Ashwin S.; Mphahlele, M.T. (Matsie Theodora); Venter, Karien; Stoltz, Anton Carel; Mathebula, R.; Masotla, T.; Van der Walt, M.; Pagano, M.; Jensen, P.; Nardell, Edward Anthony (International Union Against Tuberculosis and Lung Disease, 2014-09)
    BACKGROUND: Effective treatment for drug-susceptible tuberculosis (TB) rapidly renders patients noninfectious, long before conversion of sputum acid-fast smear or culture to negative. Multidrug-resistant TB (MDR-TB) ...
  • A rare case of massive hepatosplenomegaly due to acute lymphoblastic leukaemia in pregnancy 
    Goncalves, R.; Meel, R. (Health and Medical Publishing Group, 2017-05)
    Acute lymphoblastic leukaemia (ALL) is rarely seen in pregnancy. Massive hepatosplenomegaly as a presentation of ALL has not been described previously in any patient population. A 30-year-old pregnant woman presented at ...
  • Reactive oxidants regulate membrane repolarization and store-operated uptake of calcium by formyl peptide-activated human neutrophils 
    Tintinger, Gregory Ronald; Theron, Annette J.; Anderson, Ronald; Potjo, Moliehi (Elsevier, 2007-06-15)
    Please refer to abstract in article
  • Recent advances in the epidemiology and prevention of Streptococcus pneumoniae infections 
    Feldman, Charles; Anderson, Ronald (F1000Research, 2020)
    The introduction of pneumococcal conjugate vaccines (PCVs) 7 and 13 into national childhood immunization programs in the US in 2000 and 2010, respectively, proved to be remarkably successful in reducing infant mortality ...
  • The reliability of chest radiographs in predicting left atrial enlargement 
    Quinton, S.J. (Susanna Jacoba); Ker, James A.; Rheeder, Paul; Deffur, A. (Clinics Cardiv, 2010-09)
    INTRODUCTION: Estimates of left atrial size in patients with suspected cardiac disease play an important role in predicting prognosis and events, as well as treatment decisions. Two methods are commonly used to estimate ...
  • Reliable and cost-effective serodiagnosis of rheumatoid arthritis 
    Meyer, Pieter Willem Adriaan; Ally, Mahmood Moosa Tar Mahomed; Anderson, Ronald (Springer, 2016-06)
    Early diagnosis of patients with rheumatoid arthritis (RA) optimises therapeutic benefit and the probability of achieving disease remission. Notwithstanding clinical acumen, early diagnosis is dependent on access to reliable ...
  • Response to traditional disease-modifying anti-rheumatic drugs in indigent South Africans with early rheumatoid arthritis 
    Hodkinson, Bridget; Musenge, Eustasius; Ally, Mahmood Moosa Tar Mahomed; Meyer, Pieter Willem Adriaan; Anderson, Ronald; Tikly, Mohammed (Springer, 2012-04)
    The clinical response to traditional diseasemodifying anti-rheumatic drugs (DMARDs) in indigent South Africans with early rheumatoid arthritis was investigated. A cohort of patients with early (≤2 years) RA who ...
  • Review of pregnancy and fertility issues in women with rheumatic diseases 
    Kalpee, R. (In House Publications, 2016)
    Rheumatic diseases occur more commonly in women and often during child bearing age. SLE is 10-15 times more common in women than in men.1 Most SLE patients present with their disease between 15 and 64 years age.2 ...
  • Rheumatoid arthritis 
    Ally, Mahmood Moosa Tar Mahomed; Hodkinson, Bridget (Medpharm, 2014-05)
    Immune-mediated inflammatory disorders include a clinically diverse group of conditions that share similar pathogenic mechanisms. Conditions such as rheumatoid arthritis (RA), psoriasis, spondyloarthropathy, inflammatory ...
  • Rheumatoid Arthritis 
    Ally, Mahmood Moosa Tar Mahomed; Hodkinson, Bridget (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016)
    Immune-mediated inflammatory disorders include a clinically diverse group of conditions sharing similar pathogenic mechanisms. Conditions such as rheumatoid arthritis, psoriasis, spondyloarthropathy, inflammatory bowel ...
  • Rheumatoid arthritis 
    Visser, C.C.; Ally, Mahmood Moosa Tar Mahomed (South African Orthopaedic Association, 2010)
    RA is a chronic inflammatory disease resulting in severe morbidity and premature mortality. This review explores in a series of two articles, the current developments in the pathogenesis, diagnosis, monitoring and management ...
  • Rheumatoid arthritis and risk of cardiovascular disease 
    Meyer, Pieter Willem Adriaan; Anderson, Ronald; Ker, James A.; Ally, Mahmood Moosa Tar Mahomed (Clinics Cardive, 2018-09)
    In developing countries, rheumatoid arthritis (RA) remains a seriously under-prioritised disease, particularly among the underprivileged, often resulting in presentation of patients late in the course of their disease, ...
  • Risk factors precipitating exacerbations in adult asthma patients presenting at Kalafong Hospital, Pretoria 
    Geyser, M.M. (Mimi); Rheeder, Paul (Medpharm Publications, 2008-07)
    BACKGROUND: Research into asthma is proceeding at an unprecedented rate and yet we live with a disease that escalates in prevalence and severity, despite a greater understanding of its pathophysiology and the necessary ...
  • A risk measurement tool for targeted HIV prevention measures amongst young pregnant and lactating women in South Africa 
    Ramraj, Trisha; Abdelatif, Nada; Chirinda, Witness; Abdullah, Fareed; Kindra, Gurpreet; Goga, Ameena Ebrahim (BMC, 2022-06-30)
    BACKGROUND : We aimed to develop and validate a tool to identify which pregnant/lactating young South African women (≤ 24 years) are at risk of HIV infection. METHODS : Data from three national South African Prevention ...
  • The risk of CAD in women 
    Ker, James A. (New Media Publishing, 2018-08)
    A therosclerotic cardiovascular disease (CVD) is a chronic disorder that develops throughout life causing no symptoms. However, with progression to an advanced stage, symptoms of ischaemia appear, terminating in acute ...
  • Role and merits of green based nanocarriers in cancer treatment 
    Elbagory, Abdulrahman M.; Marima, Rahaba; Dlamini, Zodwa (MDPI, 2021-11-13)
    The use of nanocarriers for biomedical applications has been gaining interests from researchers worldwide for the delivery of therapeutics in a controlled manner. These “smart” vehicles enhance the dissolution and the ...
  • The role of imaging in rheumatoid arthritis 
    Kgoebane, Kgomotso; Ally, Mahmood Moosa Tar Mahomed; Duim-Beytell, Martha C.; Suleman, Farhana Ebrahim (Health and Medical Publishing Group, 2018-07-11)
    Conventional radiographs of the hands and feet have traditionally been used in the diagnosis, management and monitoring of patients with rheumatoid arthritis (RA). However, they are not sensitive enough to detect changes ...
  • Routine monitoring of diabetes mellitus in adults at primary health care level, and self-monitoring of blood glucose (SMBG) 
    Kemp, Tanja (Health and Medical Publishing Group, 2010-10)
    Diabetes care extends beyond glycaemic control, and several interventions to improve diabetes outcome are supported by evidence from large trials. Most of the recommendations included here are based on the Society for ...
  • Salmonella typhimurium meningitis in an adult patient with AIDS 
    Swe Swe-Han, K .; Nagel, G.; Van der Westhuizen, M.; Hoosen, Anwar Ahmed (BMJ, 2008-01)
    Salmonella meningitis is an unusual complication of Salmonella sepsis and occurs mainly in children. A rare case of Salmonella typhimurium meningitis occurring in an adult HIV positive man who presented with a history of ...
  • SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma 
    Wibmer, Constantinos Kurt; Ayres, Frances; Hermanus, Tandile; Madzivhandila, Mashudu; Kgagudi, Prudence; Oosthuysen, Brent; Lambson, Bronwen E.; De Oliveira, Tulio; Vermeulen, Marion; Van der Berg, Karin; Rossouw, Theresa M.; Boswell, Michael T.; Ueckermann, Veronica; Meiring, Susan; Von Gottberg, Anne; Cohen, Cheryl; Morris, Lynn; Bhiman, Jinal N.; Moore, Penny L. (Springer, 2021-04)
    SARS-CoV-2 501Y.V2 (B.1.351), a novel lineage of coronavirus causing COVID-19, contains substitutions in two immunodominant domains of the spike protein. Here, we show that pseudovirus expressing 501Y.V2 spike protein ...