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Browsing Research Articles (Chemical Pathology) by Title
Now showing items 38-57 of 68
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(BMJ Publishing Group, 2023-09)Ketamine, a dissociative anaesthetic drug, acts on the central nervous system (CNS) primarily through antagonism of the n-methyl-d-aspartate (NMDA) receptor. Methods of administration include intravenous, intramuscular, ...
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(Health and Medical Publishing Group, 2003-07)The older 'traditional' lipid guidelines have placed undue emphasis on individually high-risk factors such as cholesterol. The aim of the TC cut-off points of 5.2 mmol/l and 6.2 mmol/l was to identify as many subjects as ...
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(International Federation of Clinical Chemistry and Laboratory Medicine, 2022-08)The Coronavirus Disease 2019 (COVID-19) pandemic is caused by the SARS-CoV-2 RNA virus. Nucleic acid amplification testing (NAAT) is the mainstay to confirm infection. A large number of reverse transcriptase polymerase ...
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(Health and Medical Publishing Group, 2013)The editorial ‘No schools for medical editors’ struck a personal chord. The lot of the journal editor can indeed be lonely. The challenge of dealing with the manuscripts of colleagues, friends and associates is often ...
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(Elsevier, 2015-10)OBJECTIVE : The variant allele of rs3798220 in the apolipoprotein(a) gene (LPA) is used to assess the risk for coronary artery disease (CAD) in Europeans, where it is associated with short alleles of the Kringle IV-2 (KIV-2) ...
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(Clinics Cardiv, 2012-11)With the use of specific cardiac markers with higher sensitivity, new perspectives have emerged on the nature of myocardial necrosis and injury, which are associated with acute coronary syndrome (ACS). The third universal ...
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(Taylor and Francis, 2019)Ebola virus (EBOV) is a lethal human pathogen with a risk of global spread of its zoonotic infections, and Ebolavirus Zaire specifically has the highest fatality rate amongst other species. There is a need for continuous ...
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(Elsevier, 2021-03)Nipah virus (NiV) infections are highly contagious and can cause severe febrile encephalitis. An outbreak of NiV infection has reported high mortality rates in Southeast Asian countries including Bangladesh, East Timor, ...
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(AOSIS, 2023-04-14)INTRODUCTION : Liddle syndrome is an autosomal dominantly inherited disorder usually arising from single mutations of the genes that encode for the alpha, beta and gamma epithelial sodium channel (ENaC) subunits. This leads ...
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(Clinics Cardiv, 2008-09)BACKROUND: Amino terminal pro-B-type natriuretic peptide (NT-proBNP) is a sensitive marker of ventricular dysfunction. Exercise causes an increase in the secretion of NT-proBNP, and with myocardial ischaemia the increase ...
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(Elsevier, 2019-12)Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). In the present age, due to the rapid increase in antibiotic resistance worldwide, TB has become a major threat to human life. Regardless ...
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(Taylor and Francis, 2019)Ebola is a dangerous virus transmitted by animals and humans and to date there is no curable agent for such a deadly infectious disease. In this study, pharmacoinformatics-based methods were adopted to find effective novel ...
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(MDPI, 2020-12)Vitamin D is a steroid hormone crucial for bone mineral metabolism. In addition, vitamin D has pleiotropic actions in the body, including anti-cancer actions. These anti-cancer properties observed within in vitro studies ...
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Postmortem genetic testing in young individuals : what clinical medical practitioners need to know (Health and Medical Publishing Group, 2022-12)The death of a young person is most often a tragic occurrence, more so when this death was unexpected. Forensic pathologists are mandated to investigate such deaths, and there has been a strong move internationally towards ...
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(AOSIS, 2022-06-23)BACKGROUND : Formalin-fixed paraffin-embedded (FFPE) tissue archives in hospitals, biobanks, and others offer a vast collection of extensive, readily available specimens for molecular testing. Unfortunately, the use of ...
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(Spandidos Publications, 2017)Micro‑ribonucleic acids (miRNAs) are small functional non‑coding RNAs that downregulate gene expression at the post‑transcriptional level. Abnormal expression of specific miRNAs has been recorded in chronic lymphocytic ...
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Propensity of people of African descent towards hypertension-associated cardiovascular pathologies (Nature Publishing Group, 2016-06)No abstract available.
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(South African Heart Association, 2015)The SA Heart Association seeks to to improve the early management of ST-segment elevation myocardial infarction in South Africa. This pilot study was undertaken to establish the current time intervals present in the ...
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(Health and Medical Publishing Group, 2008)OBJECTIVES. To assess the effectiveness and safety of a twice-daily regimen of a generic fixed-dose combination (FDC) of stavudine, lamivudine and nevirapine (Triviro) in a cohort of Zimbabwean HIV-1-positive adults. DESIGN: ...
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(Elsevier, 2016-04)Simplified molecular input line entry system (SMILES) descriptor based quantitative structure–activity relationship (QSAR) study was performed on a set of HIV-protease inhibitors to explore the structural functionalities ...
Now showing items 38-57 of 68