• Suprasellar cyst presenting with bobble-head doll syndrome 

  George, Roshan; Gaxa, Luvo; Lockhat, Zarina I.; Hlahla, Stevens Kgomotso; Van der Meyden, Cornelis Hendrikus; Kisten, Ravendran; Bida, Meshack (Elsevier, 2020-01)

  BACKGROUND : Bobble-head doll syndrome is a rare neurological syndrome presenting with repetitive anteroposterior head movements. It is usually associated with expansile cystic lesions in the third ventricular region. CASE ...
• Potato tuber corky cracks caused by multiple Rhizoctonia species 

  Gush, Sasha-Lee (Plaas Media, 2020-07)

  Potato (Solanum tuberosum L.) is the most consumed and economically important vegetable crop in the world. Nutritionally, potato is ideal for human consumption and provides a balanced source of starch, high-quality proteins, ...
• A de novo 2.2 Mb recurrent 17q23.1q23.2 deletion unmasks novel putative regulatory non-coding SNVs associated with lethal lung hypoplasia and pulmonary hypertension : a case report 

  Karolak, Justyna A.; Gambin, Tomasz; Honey, E.M. (Engela); Slavik, Tomas; Popek, Edwina; Stankiewicz, Paweł (BioMed Central, 2020-03-06)

  BACKGROUND : Application of whole genome sequencing (WGS) enables identification of non-coding variants that play a phenotype-modifying role and are undetectable by exome sequencing. Recently, non-coding regulatory single ...
• The diagnosis of clinically significant oesophageal Candida infections : a reappraisal of clinicopathological findings 

  Hissong, Erika; Schechter, Shula; Mowers, Jonathan; Yantiss, Rhonda.K.; Slavik, Tomas; Cheng, Jerome; Lamps, Laura W. (Wiley, 2020-04)

  AIMS : Distinguishing true oesophageal Candida infections from oral contaminants is a common diagnostic issue. Historically, histological features believed to indicate true infection included epithelial invasion by ...
• Merkel cell carcinoma of the head in a young African Albino woman with HIV/HTLV-1 coinfection associated with multiple squamous cell carcinomas 

  Tenea, Daniela; Dinkel, Jurgen Erich; Becker, Jurgen C.; Van der Walt, Elizabeth (Karger, 2019)

  Merkel cell carcinoma (MCC) is a rare cutaneous neoplasm of presumed neuroendocrine origin, with aggressive behavior and poor prognosis, that tends to have an increased incidence among elderly Caucasians and immunosuppressed ...
• Uterine PEComas : a morphologic, immunohistochemical, and molecular analysis of 32 tumors 

  Bennett, Jennifer A.; Braga, Ana C.; Pinto, Andre; Van de Vijver, Koen; Cornejo, Kristine; Pesci, Anna; Zhang, Lei; Morales-Oyarvide, Vicente; Kiyokawa, Takako; Franco Zannoni, Gian; Carlson, Joseph; Slavik, Tomas; Tornos, Carmen; Antonescu, Cristina R.; Oliva, Esther (Lippincott, Williams & Wilkins, 2018-10)

  Uterine perivascular epithelioid cell tumors (PEComas) are rare neoplasms that may show overlapping morphology and immunohistochemistry with uterine smooth muscle tumors. In this study, we evaluated the morphologic, ...
• HPV types in cervical cancer tissue in South Africa : a head-to-head comparison by mRNA and DNA tests 

  Rad, Amir; Sorbye, Sveinung Wergeland; Dreyer, Greta; Hovland, Siri; Falang, Bente Marie; Louw, Melanie; Skjeldestad, Finn Egil (Lippincott, Williams and Wilkins, 2017)

  Accurate identification of human papillomavirus (HPV)-types in cervical cancer tissue may be important for tailoring tests for primary screening and types to be included in a vaccine. The aim of this study was to compare ...
• Does radiotherapy prior to surgery improve long term prognosis in pediatric colorectal cancer in lower- and upper-middle income countries with limited resources? Our experience and literature review 

  Carrim, Yacoob Omar; Gaxa, Luvo; Van der Schyff, Fransica; Bida, Nndweleni Meshack; Omar, Fareed; Lockhat, Zarina I. (Elsevier, 2017-12)

  Colorectal carcinoma in children and adolescents is extremely rare, with an annual incidence <0.3 cases per million, most frequently reported in the second decade of life. It accounts for severe morbidity and poor prognosis ...
• p16 and Ki-67 immunohistochemical staining reduces inter- and intra-observer variability in the grading of cervical squamous intraepithelial lesions of South African women 

  Solomon, Christa; Louw, Melanie; Van Aardt, M.C. (Matthys Cornelis); Dreyer, Greta (Medpharm Publications, NISC (Pty) Ltd and Informa UK Limited [trading as the Taylor & Francis Group], 2017)

  BACKGROUND : Cervical carcinoma was the second leading malignancy in South African women (following breast carcinoma) in 2010. This study aimed to correlate histopathological criteria and immunohistochemical stains in ...
• Thymoma-associated multiorgan autoimmunity with exclusive gastrointestinal tract involvement : case report and review of the literature 

  Slavik, Tomas; Potgieter, Fritz M.; Brittain, David (Springer, 2018-07)

  Thymoma-associated multiorgan autoimmunity (TAMA) is a recently delineated and rare paraneoplastic syndrome reported in patients with thymoma. The disorder is characterized by graft-versus-host disease-like pathology ...
• An endometrial histomorphometric study of CD56+ natural killer cells in women with unexplained infertility 

  Muller, M.; Kalmeier, G.; Eyal, P.; De Bruin, A.; Pool, Roger; Du Rant, C.; Ehlers, Rene; Stander, Andre; Van Schoor, Albert-Neels; Nortje, Evangeline; Du Toit, Peet J. (Health and Medical Publishing Group, 2017-09)

  BACKGROUND. The number of peripheral blood and endometrial natural killer cells varies greatly during implantation and the first trimester of pregnancy and is thought to play a role in the maintenance of a healthy pregnancy. ...
• Mammary analogue secretory carcinoma : a rare salivary gland tumour 

  Jackson, Brandon Spencer; Pratt, T.L.; Van Rooyen, A. (Health and Medical Publishing Group, 2017-04)

  Mammary analogue secretory carcinoma (MASC) is a rare and recently described tumour of the salivary glands. MASC has similar histomorphological and immunohistochemical features of secretory carcinoma of the breast. MASC ...
• Spectrum of mitochondrial genomic variation and associated clinical presentation of prostate cancer in South African men 

  McCrow, John P.; Petersen, Desiree C.; Louw, Melanie; Chan, Eva K. F.; Harmeyer, Katherine; Vecchiarelli, Stefano; Lyons, Ruth J.; Bornman, Maria S. (Riana); Hayes, Vanessa M. (Wiley, 2016-03)

  BACKGROUND : Prostate cancer incidence and mortality rates are significantly increased in African–American men, but limited studies have been performed within Sub–Saharan African populations. As mitochondria control ...
• HPV L1 capsid protein detection in high-risk human papillomavirus-positive cervical smears 

  Heunis, Nanette; Horton, A.; Richter, Karin Louise; Dreyer, Greta; Louw, Melanie (2014)

  BACKGROUND: The L1 capsid protein is a viral nuclear protein that encapsidates the human papillomavirus (HPV) DNA to build new infectious particles. Previous studies in immune-competent patients have shown that detectable ...
• A case of disseminated Candida dubliniensis in a preterm infant : the importance of early detection and management of invasive fungal infections in neonates 

  Crause, Chantelle (Health and Medical Publishing Group, 2015-01)

  This case report highlights the importance of timely diagnosis of disseminated fungal infections in neonates, as well as the increased incidence of infection with non-albicans Candida, and the association with surgical ...
• Diagnosis and predictive molecular analysis of non-small cell lung cancer in the Africa-Middle East region : challenges and strategies for improvement 

  Slavik, Tomas; Asselah, Fatima; Fakhruddin, Najla; El Khodary, Ahmed; Torjman, Fairouz; Anis, Elia; Quinn, Martin; Khankan, Azzam; Kerr, Keith M. (Elsevier, 2014-11)

  The identification of tumor biomarkers provides information on the prognosis and guides the implementation of appropriate treatment in patients with many different cancer types. In nonesmall cell lung cancer (NSCLC), ...
• Cronkhite-Canada syndrome six decades on : the many faces of an enigmatic disease 

  Slavik, Tomas; Montgomery, Elizabeth Anne (BMJ Publishing Group, 2014)

  Cronkhite–Canada syndrome is a rare gastro-enterocolopathy of uncertain aetiology first described almost 60 years ago. It is characterised by diffuse gastrointestinal polyposis sparing only the oesophagus, ectodermal ...
• Molecular characterisation of gastrointestinal stromal tumours in a South African population 

  Baker, Gillian; Babb, Chantal; Schnugh, Desmond; Nayler, Simon; Melanie, Louw; Goedhals, Jacqueline; Bringuier, Pierre-Paul; Blay, Jean-Yves; Willem, Pascale (Spandisos, 2013)

  Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the digestive tract. Pathogenesis is linked to activating mutations identified in two proto-oncogenes, v-kit Hardy/Zuckerman 4 feline ...
• Renal disease in the elderly – a new entity? 

  Louw, Melanie (Health and Medical Publishing Group, 2012-02)

  Chronic renal disease (CRD) in adults is fairly common worldwide. CRD is often associated with cardiovascular mortality, which is increasing. In adults CRD is associated with systemic hypertension, diabetes mellitus ...
• Toothy craniopharyngioma : a literature review and case report of craniopharyngioma with extensive odontogenic differentiation and tooth formation 

  Muller, Craig; Adroos, Narosha; Lockhat, Zarina I.; Slavik, Tomas; Kruger, Henk (Springer, 2011-02)

  No abstract available.

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