George, Roshan; Gaxa, Luvo; Lockhat, Zarina I.; Hlahla, Stevens Kgomotso; Van der Meyden, Cornelis Hendrikus; Kisten, Ravendran; Bida, Meshack(Elsevier, 2020-01)
BACKGROUND : Bobble-head doll syndrome is a rare neurological syndrome presenting with repetitive anteroposterior head movements. It is usually associated with expansile cystic lesions in the third ventricular region.
CASE ...
Potato (Solanum tuberosum L.) is the most consumed and economically important vegetable crop in the world. Nutritionally, potato is ideal for human consumption and provides a balanced source of starch, high-quality proteins, ...
BACKGROUND : Application of whole genome sequencing (WGS) enables identification of non-coding variants that
play a phenotype-modifying role and are undetectable by exome sequencing. Recently, non-coding regulatory
single ...
AIMS : Distinguishing true oesophageal Candida infections from oral contaminants is a common diagnostic issue. Historically, histological features believed to indicate true infection included epithelial invasion by ...
Tenea, Daniela; Dinkel, Jurgen Erich; Becker, Jurgen C.; Van der Walt, Elizabeth(Karger, 2019)
Merkel cell carcinoma (MCC) is a rare cutaneous neoplasm of presumed neuroendocrine origin, with aggressive behavior and poor prognosis, that tends to have an increased incidence among elderly Caucasians and immunosuppressed ...
Bennett, Jennifer A.; Braga, Ana C.; Pinto, Andre; Van de Vijver, Koen; Cornejo, Kristine; Pesci, Anna; Zhang, Lei; Morales-Oyarvide, Vicente; Kiyokawa, Takako; Franco Zannoni, Gian; Carlson, Joseph; Slavik, Tomas; Tornos, Carmen; Antonescu, Cristina R.; Oliva, Esther(Lippincott, Williams & Wilkins, 2018-10)
Uterine perivascular epithelioid cell tumors (PEComas) are rare neoplasms that may show overlapping morphology and immunohistochemistry with uterine smooth muscle tumors. In this study, we evaluated the morphologic, ...
Rad, Amir; Sorbye, Sveinung Wergeland; Dreyer, Greta; Hovland, Siri; Falang, Bente Marie; Louw, Melanie; Skjeldestad, Finn Egil(Lippincott, Williams and Wilkins, 2017)
Accurate identification of human papillomavirus (HPV)-types in cervical cancer tissue may be important for tailoring tests for primary
screening and types to be included in a vaccine. The aim of this study was to compare ...
Carrim, Yacoob Omar; Gaxa, Luvo; Van der Schyff, Fransica; Bida, Nndweleni Meshack; Omar, Fareed; Lockhat, Zarina I.(Elsevier, 2017-12)
Colorectal carcinoma in children and adolescents is extremely rare, with an annual incidence <0.3 cases
per million, most frequently reported in the second decade of life. It accounts for severe morbidity and
poor prognosis ...
Solomon, Christa; Louw, Melanie; Van Aardt, M.C. (Matthys Cornelis); Dreyer, Greta(Medpharm Publications, NISC (Pty) Ltd and Informa UK Limited [trading as the Taylor & Francis Group], 2017)
BACKGROUND : Cervical carcinoma was the second leading malignancy in South African women (following breast carcinoma)
in 2010. This study aimed to correlate histopathological criteria and immunohistochemical stains in ...
Slavik, Tomas; Potgieter, Fritz M.; Brittain, David(Springer, 2018-07)
Thymoma-associated multiorgan autoimmunity (TAMA) is a recently delineated and rare paraneoplastic syndrome reported in patients with thymoma. The disorder is characterized by graft-versus-host disease-like pathology ...
Muller, M.; Kalmeier, G.; Eyal, P.; De Bruin, A.; Pool, Roger; Du Rant, C.; Ehlers, Rene; Stander, Andre; Van Schoor, Albert-Neels; Nortje, Evangeline; Du Toit, Peet J.(Health and Medical Publishing Group, 2017-09)
BACKGROUND. The number of peripheral blood and endometrial natural killer cells varies greatly during implantation and the first trimester of
pregnancy and is thought to play a role in the maintenance of a healthy pregnancy. ...
Jackson, Brandon Spencer; Pratt, T.L.; Van Rooyen, A.(Health and Medical Publishing Group, 2017-04)
Mammary analogue secretory carcinoma (MASC) is a rare and recently described tumour of the salivary glands. MASC has similar
histomorphological and immunohistochemical features of secretory carcinoma of the breast. MASC ...
McCrow, John P.; Petersen, Desiree C.; Louw, Melanie; Chan, Eva K. F.; Harmeyer, Katherine; Vecchiarelli, Stefano; Lyons, Ruth J.; Bornman, Maria S. (Riana); Hayes, Vanessa M.(Wiley, 2016-03)
BACKGROUND : Prostate cancer incidence and mortality rates are significantly increased in
African–American men, but limited studies have been performed within Sub–Saharan
African populations. As mitochondria control ...
BACKGROUND: The L1 capsid protein is a viral nuclear protein that encapsidates the human papillomavirus (HPV) DNA to build
new infectious particles. Previous studies in immune-competent patients have shown that detectable ...
Crause, Chantelle(Health and Medical Publishing Group, 2015-01)
This case report highlights the importance of timely diagnosis of disseminated fungal infections in neonates, as well as the increased
incidence of infection with non-albicans Candida, and the association with surgical ...
The identification of tumor biomarkers provides information on the prognosis and guides the implementation of
appropriate treatment in patients with many different cancer types. In nonesmall cell lung cancer (NSCLC), ...
Slavik, Tomas; Montgomery, Elizabeth Anne(BMJ Publishing Group, 2014)
Cronkhite–Canada syndrome is a rare gastro-enterocolopathy
of uncertain aetiology first described
almost 60 years ago. It is characterised by diffuse
gastrointestinal polyposis sparing only the oesophagus,
ectodermal ...
Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the digestive tract. Pathogenesis is linked to activating mutations identified in two proto-oncogenes, v-kit Hardy/Zuckerman 4 feline ...
Louw, Melanie(Health and Medical Publishing Group, 2012-02)
Chronic renal disease (CRD) in adults is
fairly common worldwide. CRD is often
associated with cardiovascular mortality,
which is increasing. In adults CRD is
associated with systemic hypertension,
diabetes mellitus ...