African horse sickness virus dynamics and host responses in naturally infected horses

Show simple item record

dc.contributor.advisor Quan, Melvyn en
dc.contributor.advisor Guthrie, Alan John en
dc.contributor.postgraduate Weyer, Camilla Theresa
dc.date.accessioned 2013-09-06T22:26:08Z
dc.date.available 2011-06-21 en
dc.date.available 2013-09-06T22:26:08Z
dc.date.created 2011-04-08 en
dc.date.issued 2011-06-21 en
dc.date.submitted 2011-06-15 en
dc.description Dissertation (MSc)--University of Pretoria, 2011. en
dc.description.abstract African horse sickness (AHS) is a life threatening disease of equids caused by African horse sickness virus (AHSV), a member of the genus Orbivirus in the family Reoviridae. The virus is transmitted to horses by midges (Culicoides spp.) and the disease is most prevalent during the time of year, and in areas where the Culicoides spp. are most abundant, namely in late summer in the summer rainfall areas of the country. Whilst the clinical signs and presentation of the disease were well documented by Sir Arnold Theiler (1921), very little is known or documented about AHSV dynamics or the clinical pathological and serological responses of horses to natural infection with AHSV. This dissertation describes the history and current knowledge on AHS, and the methods and results of a prospective study on natural AHSV infection of horses, undertaken between 2009 and 2010 by the Equine Research Centre (ERC) at the University of Pretoria, Faculty of Veterinary Science, Onderstepoort. This study is the first documented study of its nature and included animals of various ages and therefore variable vaccination status. The objectives of the study were to describe the viral dynamics of AHSV infection in horses, to gain a better understanding of the clinical pathological and serological responses to natural AHS infection and to demonstrate early detection of AHS infection in horses under field conditions. en
dc.description.availability unrestricted en
dc.description.department Veterinary Tropical Diseases en
dc.identifier.citation Weyer, CT 2010, African horse sickness virus dynamics and host responses in naturally infected horses, MSc dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/25558 > en
dc.identifier.other E11/281/gm en
dc.identifier.upetdurl http://upetd.up.ac.za/thesis/available/etd-06152011-145610/ en
dc.identifier.uri http://hdl.handle.net/2263/25558
dc.language.iso en
dc.publisher University of Pretoria en_ZA
dc.rights © 2010 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. en
dc.subject African horse sickness virus (AHSV) en
dc.subject Culicoides en
dc.subject Reoviridae en
dc.subject UCTD en_US
dc.subject.lcsh Orbiviruses
dc.title African horse sickness virus dynamics and host responses in naturally infected horses en
dc.type Dissertation en


Files in this item

This item appears in the following Collection(s)

Show simple item record