Kumar, Malkeet; Okombo, John; Mambwe, Dickson; Taylor, Dale; Lawrence, Nina; Reader, Janette; Van der Watt, Mariette Elizabeth; Fontinha, Diana; Sanches-Vaz, Margarida; Bezuidenhout, Belinda C.; Lauterbach, Sonja B.; Liebenberg, Dale; Birkholtz, Lyn-Marie; Coetzer, Theresa L.; Prudêncio, Miguel; Egan, Timothy J.; Wittlin, Sergio; Chibale, Kelly
(American Chemical Society, 2019-02)
A drug repositioning approach was leveraged to derivatize astemizole (AST), an antihistamine drug whose antimalarial activity was previously identified in a high-throughput screen. The multistage activity potential against ...
