Hypoglycaemia in virulent canine babesiosis: Prevalence and risk factors

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dc.contributor.advisor Jacobson, Linda S. en
dc.contributor.advisor Schoeman, Johan P. en
dc.contributor.postgraduate Keller, Ninette en
dc.date.accessioned 2013-09-06T14:19:17Z
dc.date.available 2005-03-08 en
dc.date.available 2013-09-06T14:19:17Z
dc.date.created 2004-08-01 en
dc.date.issued 2006-03-08 en
dc.date.submitted 2005-03-08 en
dc.description Dissertation (MMedVet (Med))--University of Pretoria, 2006. en
dc.description.abstract A study was conducted to determine the prevalence of and potential risk factors for hypoglycaemia in canine babesiosis due to Babesia canis rossi. Plasma glucose concentration was measured at presentation in 250 dogs with babesiosis, of which 111 were admitted to hospital. The overall prevalence of hypoglycaemia (< 3.3 mmol/l) was 9% (23/250). Twenty-two hypoglycaemic dogs required admission, making the prevalence of hypoglycaemia in admitted cases 19.8%. Sixteen dogs had severe hypoglycaemia (¡Ü 2.2 mmol/l) of which 5 had a blood glucose < 1 mmol/l. Hyperglycaemia (> 5.6 mmol/l) was present in 38 (38/250; 5.2%) dogs of which 21 (21/250; 8.4%) were admitted and severe hyperglycaemia (> 15 mmol/l) did not occur. Risk factors for hypoglycaemia identified by univariable analysis were: Collapsed state (P < 0.00001), severe anaemia (P = 0.0002), icterus (P = 0.003), age below 6 months (P = 0.02) and vomition (P = 0.03). After logistic regression analysis, collapsed state (OR = 17.8, 95% CI: 1.9 to 171, P = 0.01) and young age (OR = 2.8, 95% CI: 0.8 to 9.7, P = 0.1) remained significantly associated with hypoglycaemia. Toy breeds and pregnant bitches were not at higher risk for hypoglycaemia than other dogs. Hypoglycaemia was only associated with overt neurological signs in two dogs. Blood glucose concentration should ideally be measured in all dogs requiring treatment for babesiosis, but is mandatory in collapsed dogs, puppies and dogs with severe anaemia, vomition or icterus. Many cases have probably been misdiagnosed, as cerebral babesiosis in the past and hypoglycaemia should be suspected in any case with coma or other neurological signs; however, this should in no circumstances be the only reason to suspect hypoglycaemia. en
dc.description.availability unrestricted en
dc.description.department Companion Animal Clinical Studies en
dc.identifier.citation Keller, N 2004, Hypoglycaemia in virulent canine babesiosis: Prevalence and risk factors, MMedVet dissertation, University of Pretoria, Pretoria, viewed yymmdd < http://hdl.handle.net/2263/23003 > en
dc.identifier.upetdurl http://upetd.up.ac.za/thesis/available/etd-03082005-092252/ en
dc.identifier.uri http://hdl.handle.net/2263/23003
dc.language.iso en
dc.publisher University of Pretoria en_ZA
dc.rights © 2004, University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. en
dc.subject No key words available en
dc.subject UCTD en_US
dc.title Hypoglycaemia in virulent canine babesiosis: Prevalence and risk factors en
dc.type Dissertation en


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